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RSV-IN-1
🥰Excellent
Catalog No. T12774Cas No. 861139-16-4
RSV-IN-1 is an inhibitor of human respiratory syncytical virus (hRSV) and reduced the virus infectivity with IC50 value of 0.11 μM.
RSV-IN-1
🥰Excellent
Catalog No. T12774Cas No. 861139-16-4
RSV-IN-1 is an inhibitor of human respiratory syncytical virus (hRSV) and reduced the virus infectivity with IC50 value of 0.11 μM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $97 | In Stock | |
| 5 mg | $222 | In Stock | |
| 10 mg | $379 | In Stock | |
| 25 mg | $626 | In Stock | |
| 50 mg | $883 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $243 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | RSV-IN-1 is an inhibitor of human respiratory syncytical virus (hRSV) and reduced the virus infectivity with IC50 value of 0.11 μM. |
| Targets&IC50 | RSV (human):0.11μM |
| In vitro | The concentration of P13 that reduces the number of RSV plaques (IC50 is 0.11 μM, in HEp-2 cells), with a CC50 of 310 μM for reducing HEp-2 cell viability, results in a selective index (CC50/IC50) of 2818. These escape plaques are smaller and exhibit a non-syncytial phenotype compared to plaques formed without the inhibitor. |
| Molecular Weight | 427.48 |
| Formula | C20H21N5O4S |
| Cas No. | 861139-16-4 |
| Smiles | COc1ccc(cc1-c1nnc2c3ccccc3c(C)nn12)S(=O)(=O)N(C)CCO |
| Relative Density. | 1.43 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 125 mg/mL (292.41 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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