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Simvastatin acid ammonium
🥰Excellent
Catalog No. T16885Cas No. 139893-43-9
Alias Tenivastatin ammonium
Simvastatin acid ammonium (Tenivastatin ammonium) is an HMG-CoA reductase (HMGCR) inhibitor that reduces cholesterol production by competitively inhibiting HMG-CoA reductase (3-hydroxy-methylglutaryl coenzyme).
Simvastatin acid ammonium
🥰Excellent
Catalog No. T16885Alias Tenivastatin ammoniumCas No. 139893-43-9
Simvastatin acid ammonium (Tenivastatin ammonium) is an HMG-CoA reductase (HMGCR) inhibitor that reduces cholesterol production by competitively inhibiting HMG-CoA reductase (3-hydroxy-methylglutaryl coenzyme).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $39 | In Stock | |
| 10 mg | $64 | In Stock | |
| 25 mg | $106 | In Stock | |
| 50 mg | $147 | In Stock | |
| 100 mg | $228 | In Stock | |
| 200 mg | $342 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Simvastatin acid ammonium (Tenivastatin ammonium) is an HMG-CoA reductase (HMGCR) inhibitor that reduces cholesterol production by competitively inhibiting HMG-CoA reductase (3-hydroxy-methylglutaryl coenzyme). |
| In vitro | Simvastatin acid ammonium (0.1-20 μM, treated for 24 h) significantly inhibited ROS production in indolephenol sulfate-treated hCM cells, with reductions ranging from 8.9% to 43%. In addition, 0.1-20 μM Simvastatin acid ammonium, treated for 24 hours, also affected the expression level of OATP3A1 protein in hCM and OATP3A1-expressing HEK293 cells. [2] |
| Alias | Tenivastatin ammonium |
| Molecular Weight | 453.61 |
| Formula | C25H43NO6 |
| Cas No. | 139893-43-9 |
| Smiles | CCC(C)(C)C(O[C@@H]1[C@@]2([H])C(C=C[C@@H]([C@@H]2CC[C@@H](O)C[C@@H](O)CC([O-])=O)C)=C[C@@H](C1)C)=O.[NH4+] |
| Relative Density. | 1.31g/cm3 |
Storage & Solubility Information
| Storage | keep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||
| Solubility Information | DMSO: 4.00 mg/mL (8.82 mM), Sonication is recommended | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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