Shopping Cart
- Remove All
Your shopping cart is currently empty
SMN-C2
Catalog No. T73475Cas No. 1446311-56-3
SMN-C2 is a selective regulator of SMN2 gene splicing, a risdiplam analogue, a selective RNA-binding ligand that regulates pre-mRNA splicing and acts by binding to SMN2 pre-mRNA.SMN-C2 has the potential to be used in the study of spinal muscular atrophy (SMA).
SMN-C2
Catalog No. T73475Cas No. 1446311-56-3
SMN-C2 is a selective regulator of SMN2 gene splicing, a risdiplam analogue, a selective RNA-binding ligand that regulates pre-mRNA splicing and acts by binding to SMN2 pre-mRNA.SMN-C2 has the potential to be used in the study of spinal muscular atrophy (SMA).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $159 | In Stock | |
| 5 mg | $395 | In Stock | |
| 10 mg | $642 | In Stock | |
| 25 mg | $993 | In Stock | |
| 50 mg | $1,330 | In Stock | |
| 100 mg | $1,780 | In Stock | |
| 500 mg | $3,620 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "SMN-C2"
Thymidine
Cited
Thymidin, NSC 21548, DThyd, Deoxyribothymidine, 5-Methyldeoxyuridine
TWP291150-89-5
Thymidine (DThyd) is a cell synchronizing agent and a specific precursor of deoxyribonucleic acid. Thymidine inhibits DNA synthesis and can cause cell cycle arrest in the G1/S phase.
- $45
Size
QTY
CitedGuanidine hydrochloride
Guanidinium chloride, Guanidine HCl, Aminoformamidine Hydrochloride, Aminoformamidine HCl
T041550-01-1
Guanidine hydrochloride (Aminoformamidine Hydrochloride) is a strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant.
- $29
Size
QTY
5-Fluorouracil Cited
NSC 19893, Fluorouracil, 5-FU, 5-Fluoracil
T098451-21-8
5-Fluorouracil (5-FU) is a uracil analog and inhibitor of DNA synthesis, exhibiting antitumor activity by affecting pyrimidine synthesis through thymidylate synthase inhibition; it induces apoptosis and autophagy.
- $30
Size
QTY
CitedRifampicin Cited
Rimactane, Rifamycin AMP, Rifampin
T068113292-46-1
Rifampicin (Rifamycin AMP) is a broad-spectrum antibiotic. Rifampicin has a strong antibacterial effect against Mycobacterium tuberculosis and is also effective against gram-positive and gram-negative bacteria and viruses.
- $45
Size
QTY
CitedFolic acid Cited
Vitamin M, Vitamin B9, Pteroylglutamic acid, Folate, Folacin
T006259-30-3
Folic acid (Vitamin B9) is a vitamin B9 that is essential for the synthesis of DNA/RNA and for the production and maintenance of new cells. Folic acid deficiency can lead to anemia, neural tube closure defects, tumors, aging, and other diseases.
- $45
Size
QTY
CitedTemozolomide
Cited
TZM, TMZ, NSC 362856, CCRG 81045
T117885622-93-1
Temozolomide (TMZ) is a DNA alkylating agent with blood-brain barrier permeability and oral activity. Temozolomide has antitumor activity and antiangiogenic activity, and also induces apoptosis and autophagy. Temozolomide is stable under acidic conditions and hydrolyzes under neutral or slightly alkaline conditions.
- $42
Size
QTY
Cited2,4-D
Macondray, Hedonal, Chloroxone, 2,4-D acid
T2094594-75-7
2,4-Dichlorophenoxyacetic acid (Hedonal) is a synthetic auxin used as a plant growth regulator and also used as a supplement in plant cell culture media. It is an active ingredient in herbicides used to disrupts the actin cytoskeleton for the control of root elongation and cell production.
- $44
Size
QTY
Ribavirin Cited
Tribavirin, RTCA, NSC-163039, ICN-1229
T068436791-04-5
Ribavirin (Tribavirin) is a synthetic nucleoside analog of ribofuranose with activity against hepatitis C virus and other RNA viruses.
- $39
Size
QTY
CitedAcyclovir Cited
Acycloguanosine, Aciclovir
T145459277-89-3
Acyclovir (Aciclovir) is a synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2, varicella-zoster virus and other viruses of the herpesvirus family.
- $39
Size
QTY
CitedResveratrol Cited
trans-Resveratrol, SRT 501
T1558501-36-0
Resveratrol (SRT 501) is a polyphenolic natural product, a plant antitoxin with antioxidant and chemopreventive activities. Resveratrol has a wide range of targets including COX, SIRT, LOC, etc. Resveratrol induces autophagy and apoptosis.
- $36
Size
QTY
CitedSelect Batch
Purity:99.01%
ee:100%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | SMN-C2 is a selective regulator of SMN2 gene splicing, a risdiplam analogue, a selective RNA-binding ligand that regulates pre-mRNA splicing and acts by binding to SMN2 pre-mRNA.SMN-C2 has the potential to be used in the study of spinal muscular atrophy (SMA). |
| In vitro | SMN-C2 (20 mg/kg/day) used in Δ7 mice (a severe model of SMA) can substitute SMN2 splicing, causing an increase in SMN protein levels in the brains and spinal cords of mice, improving mouse motor function, and extending mouse lifespan[1]. |
| Molecular Weight | 417.5 |
| Formula | C24H27N5O2 |
| Cas No. | 1446311-56-3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy SMN-C2 | purchase SMN-C2 | SMN-C2 cost | order SMN-C2 | SMN-C2 chemical structure | SMN-C2 in vitro | SMN-C2 formula | SMN-C2 molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.