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Sodium Tetradecyl Sulfate

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COA HNMR

Sodium Tetradecyl Sulfate

Catalog No. T9620Cas No. 1191-50-0

Sodium Tetradecyl Sulfate is a detergent sclerosant with antithrombotic effects and commonly used for the treatment of varicose veins.

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Pack Size	Price	Availability
25 mg	$41	In Stock
50 mg	$57	In Stock
100 mg	$82	In Stock
200 mg	$121	In Stock
1 mL x 10 mM (in DMSO)	$45	In Stock

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Product Introduction

Bioactivity

Description	Sodium Tetradecyl Sulfate is a detergent sclerosant with antithrombotic effects and commonly used for the treatment of varicose veins.
In vitro	Proteins C, S and antithrombin (AT) were assayed in normal plasma treated with increasing concentrations of Sodium Tetradecyl Sulfate. High concentration (>0.6%) Sodium Tetradecyl Sulfate significantly destroyed proteins C, S and AT. Sodium Tetradecyl Sulfate potentiated the anticoagulant effect of APC. Sodium Tetradecyl Sulfate mimicked AT and demonstrated significant anti-Xa and anti-IIa activity. STS demonstrated a weak anticoagulant profile to heparin. It also significantly potentiated the anticoagulant effect of heparin[2].
In vivo	i.v. + p.v. injection of Sodium Tetradecyl Sulfate and hydroxy polyethoxy dodecan provided a high degree of efficacy as regards vein occlusion. On the other hand, i.v. + p.v. injection induced a severe inflammation and necrosis of the tissues surrounding the sclerosed vein[3].

Chemical Properties

Molecular Weight	316.43
Formula	C14H29NaO4S
Cas No.	1191-50-0

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 65 mg/mL (204.76 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1603 mL	15.8013 mL	31.6026 mL	158.0128 mL
5 mM	0.6321 mL	3.1603 mL	6.3205 mL	31.6026 mL
10 mM	0.3160 mL	1.5801 mL	3.1603 mL	15.8013 mL
20 mM	0.1580 mL	0.7901 mL	1.5801 mL	7.9006 mL
50 mM	0.0632 mL	0.3160 mL	0.6321 mL	3.1603 mL
100 mM	0.0316 mL	0.1580 mL	0.3160 mL	1.5801 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

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mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

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Keywords

InhibitorTetradecyl sulfatevaricose veinsinhibitsclerosing agentSodium Tetradecyl Sulfate