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T-Cadinol
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Catalog No. TN7792Cas No. 5937-11-1
Alias Cedrelanol
T-Cadinol (Cedrelanol) is a sesquiterpene compound isolated from C. sylvestris that exhibits anti-Trypanosoma cruzi activity and potential anticancer activity, inhibits trypanosomes and flagellomorphs, induces dendritic cells and drives Th1 polarization in human monocytes.T-Cadinol is a calcium antagonist that relaxes the contraction of 60 mM K+ induced by T-Cadinol in a concentration-dependent manner. 60 mM K+-induced contraction.
T-Cadinol
😃Good
Catalog No. TN7792Alias CedrelanolCas No. 5937-11-1
T-Cadinol (Cedrelanol) is a sesquiterpene compound isolated from C. sylvestris that exhibits anti-Trypanosoma cruzi activity and potential anticancer activity, inhibits trypanosomes and flagellomorphs, induces dendritic cells and drives Th1 polarization in human monocytes.T-Cadinol is a calcium antagonist that relaxes the contraction of 60 mM K+ induced by T-Cadinol in a concentration-dependent manner. 60 mM K+-induced contraction.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $940 | 7-10 days | |
| 5 mg | $2,400 | 7-10 days | |
| 10 mg | $3,600 | 7-10 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | T-Cadinol (Cedrelanol) is a sesquiterpene compound isolated from C. sylvestris that exhibits anti-Trypanosoma cruzi activity and potential anticancer activity, inhibits trypanosomes and flagellomorphs, induces dendritic cells and drives Th1 polarization in human monocytes.T-Cadinol is a calcium antagonist that relaxes the contraction of 60 mM K+ induced by T-Cadinol in a concentration-dependent manner. 60 mM K+-induced contraction. |
| Targets&IC50 | T. cruzi (no-flagellate):15.8 μM, T. cruzi (trypanosome):18.2 μM |
| In vitro | T-Cadinol, a sesquiterpenoid derived from C. sylvestris, exhibited antitrypanosomal effects against Trypanosoma cruzi, with IC50 of 18.2 μM and 15.8 μM for trypanosome and no-flagellate, respectively. [1] |
| Alias | Cedrelanol |
| Molecular Weight | 222.37 |
| Formula | C15H26O |
| Cas No. | 5937-11-1 |
| Smiles | [C@@H](C)(C)[C@H]1[C@]2([C@]([C@@](C)(O)CC1)(CCC(C)=C2)[H])[H] |
Storage & Solubility Information
| Storage | keep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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