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Tasosartan

Tasosartan (WAY-ANA 756) is an antagonist of angiotensin II type 2 (AT2) receptor (IC50 = 1.2 nM).

Catalog No. T7797Cas No. 145733-36-4

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Purity:98.9%

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COA HNMR HPLC

Tasosartan

Catalog No. T7797Cas No. 145733-36-4

Tasosartan (WAY-ANA 756) is an antagonist of angiotensin II type 2 (AT2) receptor (IC50 = 1.2 nM).

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Pack Size	Price	Availability
1 mg	$51	In Stock
2 mg	$74	In Stock
5 mg	$122	In Stock
10 mg	$197	In Stock
25 mg	$333	In Stock
50 mg	$497	In Stock
100 mg	$693	In Stock
1 mL x 10 mM (in DMSO)	$133	In Stock

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Product Introduction

Bioactivity

Description	Tasosartan (WAY-ANA 756) is an antagonist of angiotensin II type 2 (AT2) receptor (IC50 = 1.2 nM).
Targets&IC50	Ang II type 2 receptor:1.2 nM
In vivo	In vivo, tasosartan (p.o. or i.v.) blocked by 80% AT1 receptors 1 to 2 h after drug administration and still had a 40% effect at 32 h.
Alias	WAY-ANA 756

Chemical Properties

Molecular Weight	411.46
Formula	C₂₃H₂₁N₇O
Cas No.	145733-36-4

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 125 mg/mL (303.80 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4304 mL	12.1518 mL	24.3037 mL	121.5185 mL
5 mM	0.4861 mL	2.4304 mL	4.8607 mL	24.3037 mL
10 mM	0.2430 mL	1.2152 mL	2.4304 mL	12.1518 mL
20 mM	0.1215 mL	0.6076 mL	1.2152 mL	6.0759 mL
50 mM	0.0486 mL	0.2430 mL	0.4861 mL	2.4304 mL
100 mM	0.0243 mL	0.1215 mL	0.2430 mL	1.2152 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc