Shopping Cart
- Remove All
- Your shopping cart is currently empty
TBK1/IKKε-IN-2 is a dual inhibitor of TBK1 and IKKε.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $84 | In Stock | |
5 mg | $198 | In Stock | |
10 mg | $322 | In Stock | |
25 mg | $513 | In Stock | |
50 mg | $695 | In Stock | |
100 mg | $892 | In Stock | |
1 mL x 10 mM (in DMSO) | $198 | In Stock |
Description | TBK1/IKKε-IN-2 is a dual inhibitor of TBK1 and IKKε. |
Targets&IC50 | TBK1:0.6 nM (IC50, at 5 μM ATP) , IKKε:3.9 nM (IC50, at 10 μM ATP) |
In vitro | TBK1/IKKε-IN-2 (Compound #1) inhibits TBK1 biochemical function in Ulight kinase assays at 5 μM and 250 μM ATP concentrations with IC50 values of 0.6 nM and 2.6 nM, respectively. It inhibits IKKε biochemical function in Ulight kinase assays at 10 μM ATP with an IC50 of 3.9 nM, and in the Panc 02.13 proliferation assay, it has an IC50 of 5 μM[1]. |
Molecular Weight | 457.52 |
Formula | C26H27N5O3 |
Cas No. | 1292310-49-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 16.5 mg/mL (36.06 mM), Sonication and heating are recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
|
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.