Shopping Cart
- Remove All
Your shopping cart is currently empty
Tetrabenazine Metabolite
Catalog No. T13133Cas No. 924854-60-4
Alias (-)-β-HTBZ, (-)-β-Dihydrotetrabenazine
Tetrabenazine Metabolite ((-)-β-HTBZ), a vesicles monoamine transporter 2 (VMAT2) inhibitor, is an active metabolite of Tetrabenazine. Tetrabenazine Metabolite has a high affinity for VMAT2 with a Ki of 13.4 nM. Tetrabenazine Metabolite is often used to study chorea associated with Huntington's disease and other hyperactivity disorders.
Tetrabenazine Metabolite
Catalog No. T13133Alias (-)-β-HTBZ, (-)-β-DihydrotetrabenazineCas No. 924854-60-4
Tetrabenazine Metabolite ((-)-β-HTBZ), a vesicles monoamine transporter 2 (VMAT2) inhibitor, is an active metabolite of Tetrabenazine. Tetrabenazine Metabolite has a high affinity for VMAT2 with a Ki of 13.4 nM. Tetrabenazine Metabolite is often used to study chorea associated with Huntington's disease and other hyperactivity disorders.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $117 | In Stock | |
| 5 mg | $268 | In Stock | |
| 10 mg | $394 | In Stock | |
| 25 mg | $592 | In Stock | |
| 50 mg | $828 | In Stock | |
| 100 mg | $1,130 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $262 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "Tetrabenazine Metabolite"
Tetrabenazine
Xenazine, Ro 1-9569
T071958-46-8
Tetrabenazine (Ro 1-9569) is a former antipsychotic drug used to treat various movement disorders. It inhibits neurotransmitter uptake into adrenergic storage vesicles and serves as a high-affinity label for the vesicle transport system.
- $30
Size
QTY
Rose Bengal sodium
Rose Bengal
T7651632-69-9
Rose Bengal sodium is a potent inhibitor of VGlut and vesicular monoamine transporter (VMAT) (Ki of 19 and 64 nM for VGlut andVMAT, respectively）
- $39
Size
QTY
Fostamatinib
R788
T6115901119-35-5
Fostamatinib (R788)(IC50 of 41 nM), which is a prodrug of the active metabolite R406, is a Syk inhibitor. It does not work on Lyn.
- $36
Size
QTY
Reserpine
Serpivite, Serpasil, Serpalan
T079150-55-5
Reserpine (Serpalan) is an alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
- $36
Size
QTY
(+)-Tetrabenazine
(3R,11bR)-Tetrabenazine, (3R,11bR)-TBZ, (+)-TBZ
T131341026016-83-0
(+)-Tetrabenazine ((3R,11bR)-Tetrabenazine) is a reversible vesicular monoamine transporter 2 (VMAT-2) inhibitor, inhibits transport by VMAT2 with 10-fold greater potency than transport by VMAT1.
- $47
Size
QTY
Nisoxetine hydrochloride
T2307057754-86-6
Nisoxetine hydrochloride is a noradrenaline transporter (NET) inhibitor
- $64
Size
QTY
NBI-98782
(+)-α-Dihydrotetrabenazine, (+)-α-DHTBZ, (+)-DTBZ
T756385081-18-1
NBI-98782 ((+)-α-DHTBZ) is an inhibtior of vesicular monoamine transporter (VMAT2) (Ki: 0.97 nM)
- $68
Size
QTY
FFN 206 dihydrochloride
T411951883548-88-6In house
FFN 206 dihydrochloride is a fluorescent VMAT2 substrate that can be used to detect VMAT2 subcellular sites in cell culture and shows no detectable inhibition of DAT.
- $79
Size
QTY
(+)-Kavain
L-KAWAIN, Kavain, (R)-KAWAIN
T4590500-64-1
(+)-Kavain ((R)-KAWAIN) is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.
- $39
Size
QTY
Valbenazine
NBI-98854
T71471025504-45-3
Valbenazine (NBI-98854), a highly selective vesicular monoamine transporter 2(VMAT2) inhibitor, is approved for the treatment of tardive dyskinesia.
- $46
Size
QTY
Tetrabenazine Racemate
TETRABENAZINE, Rubigen, Ro 1-9569 Racemate, Nitoman
T3534718635-93-9
Tetrabenazine Racemate (Rubigen) is a selective and reversible inhibitor of vesicular monoamine transporter-2 (VMAT-2). Tetrabenazine Racemate blocks neurotransmitter uptake into adrenergic storage vesicles and has been used as a high-affinity label for the vesicle transport system.
- $46
Size
QTY
Xanthoangelol
T1335462949-76-2
Xanthoangelol, which can be extracted from Angelica keiskei, inhibits obesity-induced inflammatory responses.Xanthoangelol has antimicrobial activity, inhibits monoamine oxidase, and induces apoptosis in neuroblastoma and leukemia cells.
- $123
Size
QTY
Select Batch
Purity:95.07%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Tetrabenazine Metabolite ((-)-β-HTBZ), a vesicles monoamine transporter 2 (VMAT2) inhibitor, is an active metabolite of Tetrabenazine. Tetrabenazine Metabolite has a high affinity for VMAT2 with a Ki of 13.4 nM. Tetrabenazine Metabolite is often used to study chorea associated with Huntington's disease and other hyperactivity disorders. |
| Targets&IC50 | VMAT2:13.4 nM |
| Alias | (-)-β-HTBZ, (-)-β-Dihydrotetrabenazine |
| Molecular Weight | 319.44 |
| Formula | C19H29NO3 |
| Cas No. | 924854-60-4 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 32.5 mg/mL (101.74 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Tetrabenazine Metabolite | purchase Tetrabenazine Metabolite | Tetrabenazine Metabolite cost | order Tetrabenazine Metabolite | Tetrabenazine Metabolite chemical structure | Tetrabenazine Metabolite formula | Tetrabenazine Metabolite molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.