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Nisoxetine hydrochloride

Catalog No. T23070Cas No. 57754-86-6

Nisoxetine hydrochloride is a noradrenaline transporter (NET) inhibitor

Nisoxetine hydrochloride

Nisoxetine hydrochloride

Purity: 98.52%
Catalog No. T23070Cas No. 57754-86-6
Nisoxetine hydrochloride is a noradrenaline transporter (NET) inhibitor
Pack SizePriceAvailabilityQuantity
5 mg$64In Stock
10 mg$97In Stock
25 mg$178In Stock
50 mg$288In Stock
100 mg$457In Stock
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Purity:98.52%
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Product Introduction

Bioactivity
Description
Nisoxetine hydrochloride is a noradrenaline transporter (NET) inhibitor
Targets&IC50
NET:Kd: 0.76 nM
Chemical Properties
Molecular Weight307.82
FormulaC17H21NO2·HCl
Cas No.57754-86-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 45 mg/mL (146.19 mM)
H2O: < 30.78 mg/mL
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.2487 mL16.2433 mL32.4865 mL162.4326 mL
5 mM0.6497 mL3.2487 mL6.4973 mL32.4865 mL
10 mM0.3249 mL1.6243 mL3.2487 mL16.2433 mL
20 mM0.1624 mL0.8122 mL1.6243 mL8.1216 mL
50 mM0.0650 mL0.3249 mL0.6497 mL3.2487 mL
100 mM0.0325 mL0.1624 mL0.3249 mL1.6243 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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