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Tetramethylkaempferol
🥰Excellent
Catalog No. TN5137Cas No. 16692-52-7
Tetramethylkaempferol is a PPARγ agonist, it can improve insulin sensitivity by increasing the levels of adiponectin, an important adipocytokine associated with insulin sensitivity in adipose tissue. Tetramethylkaempferol can concentration-dependently enhance the accumulation of triglyceride, a marker of adipogenesis.
Tetramethylkaempferol
🥰Excellent
Purity: 99.57%
Catalog No. TN5137Cas No. 16692-52-7
Tetramethylkaempferol is a PPARγ agonist, it can improve insulin sensitivity by increasing the levels of adiponectin, an important adipocytokine associated with insulin sensitivity in adipose tissue. Tetramethylkaempferol can concentration-dependently enhance the accumulation of triglyceride, a marker of adipogenesis.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $106 | In Stock | |
| 5 mg | $239 | In Stock | |
| 10 mg | $355 | In Stock | |
| 25 mg | $588 | In Stock | |
| 50 mg | $838 | In Stock | |
| 100 mg | $1,130 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $273 | In Stock |
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Purity:99.57%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Tetramethylkaempferol is a PPARγ agonist, it can improve insulin sensitivity by increasing the levels of adiponectin, an important adipocytokine associated with insulin sensitivity in adipose tissue. Tetramethylkaempferol can concentration-dependently enh |
| In vitro | Potent ligands of peroxisome proliferator-activated receptor γ (PPARγ) such as thiazolidinediones (pioglitazone, troglitazone, etc.) improve insulin sensitivity by increasing the levels of adiponectin, an important adipocytokine associated with insulin sensitivity in adipose tissue. Several constituents from medicinal plants were recently reported to show PPARγ agonist-like activity in 3T3-L1 cells, but did not show agonistic activity at the receptor site different from thiazolidinediones. |
| Molecular Weight | 342.34 |
| Formula | C19H18O6 |
| Cas No. | 16692-52-7 |
| Smiles | O(C)C1=C2C(OC(=C(OC)C2=O)C3=CC=C(OC)C=C3)=CC(OC)=C1 |
| Relative Density. | 1.29 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | Acetonitrile: 13.69 mg/mL (40 mM), Sonication is recommended.  H2O: Insoluble DMSO: 27.5 mg/ml (80.33 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
Acetonitrile/DMSO
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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