Shopping Cart
- Remove All
Your shopping cart is currently empty
Thalifoline
😃Good
Catalog No. TN5139Cas No. 21796-15-6
Thalifoline shows antifungal activity, with 100 ug against Fusarium oxysporum f. sp. lycopersici.
Thalifoline
😃Good
Catalog No. TN5139Cas No. 21796-15-6
Thalifoline shows antifungal activity, with 100 ug against Fusarium oxysporum f. sp. lycopersici.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $1,598 | Backorder | |
| 1 mL x 10 mM (in DMSO) | $1,980 | Backorder |
Bulk & Custom
Add to Cart
Questions
QHow do you ensure the quality and purity of compounds?
AThe structure of compounds is confirmed through HNMR and purity is verified through HPLC or LCMS, with most compounds having a purity of over 98%. Each batch comes with a Certificate of Analysis (COA), and testing reports are also displayed on our official website.
QHow much inhibitor should be added in cell experiments?
AIt is recommended to refer to literatures of experiments conducted using the same model. In addition, it is also necessary to determine the optimal working concentration (concentration gradient) through pre-experiments by constructing a dose-response curve. Similarly, the optimal incubation time (time gradient) should be determined through a time-course experiment. Moreover, the amount of inhibitor used is influenced by various factors, including the accessibility of the target, cell permeability, incubation time, cell type, and others. We recommend determining the initial concentration of the inhibitor by referring to the literatures.
If the Ki or IC50 are reported, it is recommended to start with 5-10 times their reported values to achieve the optimal inhibition of enzyme activity.
If the Ki or IC50 are unknown, the inhibitor concentrations should be tested, and the Ki value can be calculated using Michaelis-Menten kinetics.
Typically, the solvent used for dissolving the inhibitor is used as a control to eliminate the non-specific effects of the solvent.
QHow to store inhibitor products?
ASolid-form products can be stored at -20°C for more than 3 years.
Stock solutions are typically stored at -80°C and can be stored for more than 1 year. It is recommended to aliquot the product to avoid repeated freeze-thaw cycles.
For short-term storage, samples can be kept at 4°C for more than one week.
QHow to deal with the insoluble impurities in the product?
AInsoluble impurities, which do not affect the product activity, are recommended to filter out or remove. We will investigate to confirm whether the impurity was introduced during packaging or if it is inherent to the product itself.
QCan the inhibitor DMSO stock solution be directly diluted with buffer to create a gradient?
AIn most cases, it can dissolve. However, sometimes organic reagents may precipitate when directly added to an aqueous medium. It is recommended to first dilute the inhibitor with DMSO to form a gradient, and then add the diluted inhibitor to the buffer or cell culture medium. Some inhibitors may only dissolve in the aqueous phase at their working concentrations.
For example, if a final concentration of 1 μM is desired in cell experiments, the 10 mM DMSO stock solution can be diluted to 1 mM with DMSO, and then 2 μL can be drawn and added to 2 mL of saline/PBS/cell culture medium, resulting in a final concentration of 1 μM.
To avoid precipitation of the drug, it is recommended to preheat the mother liquor and culture medium to 37°C before dilution to avoid serious precipitation caused by low temperature. If precipitation occurs during the dilution process, it is suggested to use ultrasonic heating to redissolve the compound.
Inhibitors Related to "Thalifoline"
Chlorhexidine diacetate
Hibitane diacetate, Chlorhexidine Acetate, Bactigras
T1000L56-95-1
Chlorhexidine diacetate (Bactigras) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.
- $39
Size
QTY
Econazole nitrate
NSC 243115
T0444L24169-02-6
Econazole nitrate (NSC-243115) (Spectazole) is an imidazole class antifungal medicine.
- $30
Size
QTY
Ganciclovir
Cited
RS-21592, BW 759, 2'-Nor-2'-deoxyguanosine
T068882410-32-0
Ganciclovir (2'-Nor-2'-deoxyguanosine) is an ACYCLOVIR analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
- $51
Size
QTY
CitedChlorhexidine Cited
Rotersept, Nolvasan, Chlorhexidinum
T100055-56-1
Chlorhexidine (Rotersept) is a biguanide compound used as an antiseptic agent with topical antibacterial activity. Chlorhexidine is positively charged and reacts with the negatively charged microbial cell surface, thereby destroying the integrity of the cell membrane. Subsequently, chlorhexidine penetrates into the cell and causes leakage of intracellular components leading to cell death. Since gram-positive bacteria are more negatively charged, they are more sensitive to this agent.
- $36
Size
QTY
CitedFluconazole Cited
UK-49858
T138886386-73-4
Fluconazole (UK-49858) is a triazole antifungal agent used to treat oropharyngeal candidiasis and cryptococcal meningitis in AIDS.
- $36
Size
QTY
CitedMetronidazole Cited
Metronidazol, Flagyl, Anagiardil
T1079443-48-1
Metronidazole (Metronidazol) is a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities.
- $30
Size
QTY
CitedGanciclovir sodium
RS-21592 sodium, Cytovene IV sodium, BW 759 sodium, 2'-Nor-2'-deoxyguanosine sodium
T22337107910-75-8
Ganciclovir sodium (Cytovene IV sodium) is the sodium salt of Ganciclovir with antiviral activity, especially against cytomegalovirus (CMV) and herpes simplex virus type 1 (HSV-1).
- $40
Size
QTY
Miconazole Cited
R18134
T034422916-47-8
Miconazole (R18134) is an imidazole antifungal agent used both topically and via intravenous infusion.
- $39
Size
QTY
CitedClotrimazole Cited
FB 5097, BAY b 5097
T050623593-75-1
Clotrimazole (FB 5097), an imidazole derivative with a broad spectrum of antimycotic activity, inhibits biosynthesis of the sterol ergostol.
- $45
Size
QTY
CitedL-Lysine
Lysine Acid, lysine, Aminutrin
T2A249856-87-1
L-Lysine (Aminutrin) is one of nine essential amino acids in humans required for growth and tissue repair, Lysine is supplied by many foods, especially red meats, fish, and dairy products. Lysine seems to be active against herpes simplex viruses and present in many forms of diet supplements. The mechanism underlying this effect is based on the viral need for amino acid arginine; lysine competes with arginine for absorption and entry into cells. Lysine inhibits HSV growth by knocking out arginine.
- $42
Size
QTY
Idoxuridine
SKF 14287, NSC 39661, IDU, Dendrid, 5-IUdR, 5-Iodo-2′-deoxyuridine
T086354-42-2
Idoxuridine (Dendrid) is an analog of DEOXYURIDINE that inhibits viral DNA synthesis. The drug is used as an antiviral agent.
- $30
Size
QTY
1-Docosanol
n-Docosanol, Docosanol, Behenyl alcohol, Behenic alcohol
T0884661-19-8
1-Docosanol (Behenic alcohol) is a saturated 22-carbon aliphatic alcohol with antiviral activity. 1-Docosanol has a distinct mechanism of action and inhibits fusion between the plasma membrane and the herpes simplex virus envelope, thereby preventing viral entry into cells and subsequent viral activity and replication. 1-Docosanol is used topically in the treatment of recurrent herpes simplex labialis episodes and relieves associated pain and may help heal sores faster.
- $34
Size
QTY
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Thalifoline shows antifungal activity, with 100 ug against Fusarium oxysporum f. sp. lycopersici. |
| Molecular Weight | 207.229 |
| Formula | C11H13NO3 |
| Cas No. | 21796-15-6 |
| Relative Density. | 1.31g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
References
1.Ferens DM, Yin L, Bron R, Hunne B, Ohashi-Doi K, Kitchener PD, Sanger GJ, Witherington J, Shimizu Y, Furness JB. Functional and in situ hybridization evidence that preganglionic sympathetic vasoconstrictor neurons express ghrelin receptors. Neuroscience. 2010 Mar 17;166(2):671-9. doi: 10.1016/j.neuroscience.2010.01.001. Epub 2010 Jan 6. PubMed PMID: 20060438.2.Atcha Z, Chen WS, Ong AB, Wong FK, Neo A, Browne ER, Witherington J, Pemberton DJ. Cognitive enhancing effects of ghrelin receptor agonists. Psychopharmacology (Berl). 2009 Oct;206(3):415-27. doi: 10.1007/s00213-009-1620-6. Epub 2009 Aug 4. PubMed PMID: 19652956.
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Thalifoline | purchase Thalifoline | Thalifoline cost | order Thalifoline | Thalifoline chemical structure | Thalifoline formula | Thalifoline molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.