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UCPH-101
Catalog No. T4138Cas No. 1118460-77-7
Alias UCPH 101
UCPH-101 is an inhibitor of excitatory amino acid transporter subtype 1 (EAAT1) with an IC50 of 0.66 μM.
UCPH-101
Catalog No. T4138Alias UCPH 101Cas No. 1118460-77-7
UCPH-101 is an inhibitor of excitatory amino acid transporter subtype 1 (EAAT1) with an IC50 of 0.66 μM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $45 | In Stock | |
| 2 mg | $81 | In Stock | |
| 5 mg | $148 | In Stock | |
| 10 mg | $255 | In Stock | |
| 25 mg | $536 | In Stock | |
| 50 mg | $773 | In Stock | |
| 100 mg | $1,080 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $163 | In Stock |
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Purity:≥98%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | UCPH-101 is an inhibitor of excitatory amino acid transporter subtype 1 (EAAT1) with an IC50 of 0.66 μM. |
| Targets&IC50 | EAAT1:0.66 μM. |
| In vitro | Preincubation with 100 μM UCPH-101 results in a notable reduction in the expression levels of HA-EAAT1 and HA-GLAST. Additionally, UCPH-101 and UCPH-102 exhibit concentration-dependent inhibition of EAAT1 anion currents, with dissociation constant (KD) values of 0.34±0.03 μM (Hill=1.3±0.13, n≥9) for UCPH-101 and 0.17±0.02 μM (Hill=0.97±0.11, n≥7) for UCPH-102. |
| Alias | UCPH 101 |
| Molecular Weight | 422.48 |
| Formula | C27H22N2O3 |
| Cas No. | 1118460-77-7 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 10.6 mg/mL (25 mM) | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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