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USP5-IN-1 (compound 64) is a potent deubiquitinase USP5 inhibitor that binds to the USP5 ZnF-UBD with a KD of 2.8 μM and is selective over nine proteins containing structurally similar ZnF-UBD domains. Additionally, USP5-IN-1 inhibits the USP5 catalytic cleavage of a di-ubiquitin substrate [1].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $80 | In Stock | |
5 mg | $247 | In Stock | |
10 mg | $372 | In Stock | |
25 mg | $788 | In Stock | |
50 mg | $1,080 | In Stock | |
100 mg | $1,480 | In Stock | |
500 mg | $2,970 | In Stock |
Description | USP5-IN-1 (compound 64) is a potent deubiquitinase USP5 inhibitor that binds to the USP5 ZnF-UBD with a KD of 2.8 μM and is selective over nine proteins containing structurally similar ZnF-UBD domains. Additionally, USP5-IN-1 inhibits the USP5 catalytic cleavage of a di-ubiquitin substrate [1]. |
Molecular Weight | 437.9 |
Formula | C19H20ClN3O5S |
Smiles | O=C(O)CNC(=O)C1=CC=C(S(=O)(=O)N2CCC(C3=CC=C(Cl)C=C3)CC2)C=N1 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 112.5 mg/mL (256.9 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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