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USP30 inhibitor 11

USP30 inhibitor 11 (USP30-IN-11) is a selective USP30 inhibitor (IC50: 0.01 µΜ) that inhibits SVA and can be used in studies of cancer, mitochondrial dysfunction and Parkinson's.

Catalog No. T13267Cas No. 2067332-64-1

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Purity:100%

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USP30 inhibitor 11

Catalog No. T13267Cas No. 2067332-64-1

USP30 inhibitor 11 (USP30-IN-11) is a selective USP30 inhibitor (IC50: 0.01 µΜ) that inhibits SVA and can be used in studies of cancer, mitochondrial dysfunction and Parkinson's.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
1 mg	$215	In Stock
5 mg	$538	In Stock
10 mg	$793	In Stock
25 mg	$1,180	In Stock
50 mg	$1,630	In Stock
100 mg	$2,190	In Stock

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Product Introduction

Bioactivity

Description	USP30 inhibitor 11 (USP30-IN-11) is a selective USP30 inhibitor (IC50: 0.01 µΜ) that inhibits SVA and can be used in studies of cancer, mitochondrial dysfunction and Parkinson's.
Targets&IC50	USP30:0.01 µΜ
In vitro	In the mitochondrial outer membrane, USP30 is a 517 amino acid protein found. It is the sole deubiquitylating enzyme bearing a mitochondrial addressing signal and has been shown to deubiquitylate a number of mitochondrial proteins[1].USP30 inhibitor 11 inhibits USP30 biochemical activity with an IC50 of 0.01 µΜ in a USP30 biochemical IC50 assay (0.01-30 µΜ; λEx=540 nm; λEm=590 nm) [1].
Alias	USP30-IN-11

Chemical Properties

Molecular Weight	368.41
Formula	C₁₇H₁₆N₆O₂S
Cas No.	2067332-64-1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 20 mg/mL (54.29 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7144 mL	13.5718 mL	27.1437 mL	135.7184 mL
5 mM	0.5429 mL	2.7144 mL	5.4287 mL	27.1437 mL
10 mM	0.2714 mL	1.3572 mL	2.7144 mL	13.5718 mL
20 mM	0.1357 mL	0.6786 mL	1.3572 mL	6.7859 mL
50 mM	0.0543 mL	0.2714 mL	0.5429 mL	2.7144 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Tech Support

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