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USP15-IN-1

USP15-IN-1
USP15-IN-1 is a potent USP15 inhibitor (IC50 is 3.76 μM) with high antiproliferative activity against non-small cell lung cancer and leukemia cells. As an interacting protein of cGAS, USP15 promotes cGAS to recognize DNA and activate downstream signaling pathways.
Catalog No. T61575Cas No. 2260826-16-0
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Purity:99.81%
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USP15-IN-1

Catalog No. T61575Cas No. 2260826-16-0
USP15-IN-1 is a potent USP15 inhibitor (IC50 is 3.76 μM) with high antiproliferative activity against non-small cell lung cancer and leukemia cells. As an interacting protein of cGAS, USP15 promotes cGAS to recognize DNA and activate downstream signaling pathways.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$128In Stock
5 mg$322In Stock
10 mg$511In Stock
25 mg$829In Stock
50 mg$1,150In Stock
100 mg$1,550In Stock
500 mg$2,970In Stock
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Product Introduction

Bioactivity
Description
USP15-IN-1 is a potent USP15 inhibitor (IC50 is 3.76 μM) with high antiproliferative activity against non-small cell lung cancer and leukemia cells. As an interacting protein of cGAS, USP15 promotes cGAS to recognize DNA and activate downstream signaling pathways.
Targets&IC50
USP15:3.76 μM
In vitro
USP15-IN-1 (0.001-5 μM; 48 h) demonstrates significant inhibitory effects on the proliferation of non-small cell lung carcinoma and leukemia cells, as reported in.[1]
Chemical Properties
Molecular Weight377.44
FormulaC22H23N3O3
Cas No.2260826-16-0
Storage & Solubility Information
StorageShipping with blue ice.
Solubility Information
DMSO: 90.0 mg/mL (238.4 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6494 mL13.2471 mL26.4943 mL132.4714 mL
5 mM0.5299 mL2.6494 mL5.2989 mL26.4943 mL
10 mM0.2649 mL1.3247 mL2.6494 mL13.2471 mL
20 mM0.1325 mL0.6624 mL1.3247 mL6.6236 mL
50 mM0.0530 mL0.2649 mL0.5299 mL2.6494 mL
100 mM0.0265 mL0.1325 mL0.2649 mL1.3247 mL

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