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Vapendavir diphosphate (BTA798 diphosphate) is a rhinoceros/enterovirus inhibitor that targets the hydrophobic pocket in the viral capsid and is a capsid-binding agent with antiviral activity that prevents viral entry into the cell. Vapendavir diphosphate inhibits EV71 replication.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $670 | 6-8 weeks | |
50 mg | $871 | 6-8 weeks | |
100 mg | $1,470 | 6-8 weeks |
Description | Vapendavir diphosphate (BTA798 diphosphate) is a rhinoceros/enterovirus inhibitor that targets the hydrophobic pocket in the viral capsid and is a capsid-binding agent with antiviral activity that prevents viral entry into the cell. Vapendavir diphosphate inhibits EV71 replication. |
Targets&IC50 | EV71 (various strains):0.5-1.4 μM (EC50) |
In vitro | Vapendavir diphosphate exhibits potent antiviral activity against enterovirus 71 (EV71) replication with EC50 values ranging from 0.5-1.4 μM for different EV71 strains. [1] Vapendavir diphosphate was able to effectively inhibit the replication of 21 EV71 strains/isolates representing different genomic groups A, B and C in vitro. [2] |
Alias | BTA798 diphosphate, BTA 798 diphosphate |
Molecular Weight | 578.45 |
Formula | C21H32N4O11P2 |
Cas No. | 1198151-75-5 |
Smiles | O=P(O)(O)O.CCOC1=NOC2=C1C=CC(OCCC(CC3)CCN3C4=NN=C(C)C=C4)=C2.O=P(O)(O)O |
Relative Density. | no data available |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||
Solubility Information | DMSO: 4 mg/mL (6.92 mM), Sonication is recommended. | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
DMSO
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