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(RS)-AMPA
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Catalog No. T16800Cas No. 77521-29-0
Alias (±)-AMPA
(RS)-AMPA ((±)-AMPA) is a glutamate analog and an agonist of the effective and selective excitatory neurotransmitter L-glutamic acid.
(RS)-AMPA
😃Good
Catalog No. T16800Alias (±)-AMPACas No. 77521-29-0
(RS)-AMPA ((±)-AMPA) is a glutamate analog and an agonist of the effective and selective excitatory neurotransmitter L-glutamic acid.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | 3.581 € | 10-14 weeks | |
| 50 mg | 4.731 € | 10-14 weeks | |
| 100 mg | 6.650 € | 10-14 weeks |
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Product Introduction
Bioactivity
Chemical Properties
| Description | (RS)-AMPA ((±)-AMPA) is a glutamate analog and an agonist of the effective and selective excitatory neurotransmitter L-glutamic acid. |
| In vitro | (RS)-AMPA activates glutamate/quisqualate receptors to induce depolarizing effects without influencing NMDA receptors. It enhances the discharge rate of spontaneously active neurons or triggers a brief burst of action potentials in inactive cells. The depolarization effect of (RS)-AMPA is dose-dependent but shows significant variability across different neurons. At concentrations of 10^-3 to 10^-4 M, (RS)-AMPA causes depolarizations in cultured rat spinal and brainstem neurons. Lower concentrations (10^-5 M) result in minimal depolarizations (3-7 mV), while higher concentrations (10^-4 M) generate larger depolarizations, varying from 4 to 33 mV [1]. |
| Alias | (±)-AMPA |
| Molecular Weight | 186.17 |
| Formula | C7H10N2O4 |
| Cas No. | 77521-29-0 |
| Smiles | C(C(C(O)=O)N)C=1C(=O)NOC1C |
| Relative Density. | 1.386 g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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