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1,2,3,6-Tetragalloylglucose

🥰Excellent
Catalog No. TN1160Cas No. 79886-50-3
Alias TeGG, 1,2,3,6-Tetra-O-galloyl-β-D-glucose

1,2,3,6-Tetragalloylglucose (TeGG) has antioxidative activity, it also shows the most potent anticomplement activity (IC50 = 34 microM). 1,2,3,6-Tetragalloylglucose is also a potent inhibitor of UDP glucuronosyltransferase 1 A1 (UGT1A1, Ki = 1.68 μM).

1,2,3,6-Tetragalloylglucose

1,2,3,6-Tetragalloylglucose

🥰Excellent
Purity: 98.43%
Catalog No. TN1160Alias TeGG, 1,2,3,6-Tetra-O-galloyl-β-D-glucoseCas No. 79886-50-3
1,2,3,6-Tetragalloylglucose (TeGG) has antioxidative activity, it also shows the most potent anticomplement activity (IC50 = 34 microM). 1,2,3,6-Tetragalloylglucose is also a potent inhibitor of UDP glucuronosyltransferase 1 A1 (UGT1A1, Ki = 1.68 μM).
Pack SizePriceAvailabilityQuantity
1 mg186 €In Stock
5 mg472 €In Stock
10 mg689 €In Stock
25 mg1.073 €In Stock
50 mg1.444 €In Stock
1 mL x 10 mM (in DMSO)740 €In Stock
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Purity:98.43%
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Product Introduction

Bioactivity
Description
1,2,3,6-Tetragalloylglucose (TeGG) has antioxidative activity, it also shows the most potent anticomplement activity (IC50 = 34 microM). 1,2,3,6-Tetragalloylglucose is also a potent inhibitor of UDP glucuronosyltransferase 1 A1 (UGT1A1, Ki = 1.68 μM).
Targets&IC50
Anticomplement activity:34 microM, UGT1A1:1.68 μM(Ki)
In vitro
Two phenolics, 1,2,6-trigalloylglucose (1) and 1,2,3,6-Tetragalloylglucose (2), isolated from the stem-bark of Juglans mandshurica were evaluated for their antioxidative activities. The results showed that compounds 1 and 1,2,3,6-Tetragalloylglucose exhibited strong scavenging activities against 1,1'-diphenyl-1-picrylhydrazyl (DPPH), 2,2'-azino-bis-(3-ethylbenzenthiazoline-6-sulphonic) acid (ABTS(*+)), and superoxide radicals (O(2)(*-)), and also had a significant inhibitory effect on lipid peroxidation and low-density lipoprotein (LDL) oxidation[1]
AliasTeGG, 1,2,3,6-Tetra-O-galloyl-β-D-glucose
Chemical Properties
Molecular Weight788.57
FormulaC34H28O22
Cas No.79886-50-3
SmilesO[C@@H]1[C@@H](COC(=O)c2cc(O)c(O)c(O)c2)O[C@@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@H]1OC(=O)c1cc(O)c(O)c(O)c1
Relative Density.2.02 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 91 mg/mL (115.40 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.2681 mL6.3406 mL12.6812 mL63.4059 mL
5 mM0.2536 mL1.2681 mL2.5362 mL12.6812 mL
10 mM0.1268 mL0.6341 mL1.2681 mL6.3406 mL
20 mM0.0634 mL0.3170 mL0.6341 mL3.1703 mL
50 mM0.0254 mL0.1268 mL0.2536 mL1.2681 mL
100 mM0.0127 mL0.0634 mL0.1268 mL0.6341 mL

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