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1,3-Dicaffeoylquinic acid

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Catalog No. T5736Cas No. 19870-46-3
Alias CYNARIN, Cyclohexanecarboxyli​c acid, 1,​3-​bis[[3-​(3,​4-​dihydroxyphenyl)​-​1-​oxo-​2-​propen-​1-​yl]​oxy]​-​4,​5-​dihydroxy-​, (1S,​3R,​4R,​5R)​-, 1,5-Dicaffeoylquinic acid, 1,3-O-Dicaffeoylquinic acid

1,3-Dicaffeoylquinic acid (CYNARIN) is a natural product. It shows antioxidant and choleretic properties and is a potential immunosuppressive agent.

1,3-Dicaffeoylquinic acid

1,3-Dicaffeoylquinic acid

🥰Excellent
Purity: 98.68%
Catalog No. T5736Alias CYNARIN, Cyclohexanecarboxyli​c acid, 1,​3-​bis[[3-​(3,​4-​dihydroxyphenyl)​-​1-​oxo-​2-​propen-​1-​yl]​oxy]​-​4,​5-​dihydroxy-​, (1S,​3R,​4R,​5R)​-, 1,5-Dicaffeoylquinic acid, 1,3-O-Dicaffeoylquinic acidCas No. 19870-46-3
1,3-Dicaffeoylquinic acid (CYNARIN) is a natural product. It shows antioxidant and choleretic properties and is a potential immunosuppressive agent.
Pack SizePriceAvailabilityQuantity
20 mg133 €In Stock
1 mL x 10 mM (in DMSO)104 €In Stock
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Purity:98.68%
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Product Introduction

Bioactivity
Description
1,3-Dicaffeoylquinic acid (CYNARIN) is a natural product. It shows antioxidant and choleretic properties and is a potential immunosuppressive agent.
In vivo
CYNARIN have neuroprotective effects.CYNARIN prevents Aβ(42)-induced neurotoxicity through the activation of PI3K/Akt followed by the stimulation of Trk A, then the inhibition of GSK3β as well as the modulation of Bcl-2/Bax.
Animal Research
The neuroprotective effects of 1,5-DQA against amyloid β(1-42) (Aβ(42))-induced neurotoxicity in primary neuronal culture. To evaluate the neuroprotective effects of 1,5-DQA, primary cultured cortical neurons from neonate rats were pretreated with 1,5-DQA for 2 hours and then treated with 40 μmol/L Aβ(42) for 6 hours. Cell counting kit-8, Hoechst staining and Western blotting were used for detecting the protective mechanism. Comparisons between two groups were evaluated by independent t test, and multiple comparisons were analyzed by one-way analysis of variance (ANOVA).
AliasCYNARIN, Cyclohexanecarboxyli​c acid, 1,​3-​bis[[3-​(3,​4-​dihydroxyphenyl)​-​1-​oxo-​2-​propen-​1-​yl]​oxy]​-​4,​5-​dihydroxy-​, (1S,​3R,​4R,​5R)​-, 1,5-Dicaffeoylquinic acid, 1,3-O-Dicaffeoylquinic acid
Chemical Properties
Molecular Weight516.45
FormulaC25H24O12
Cas No.19870-46-3
SmilesO[C@@H]1C[C@@](C[C@@H](OC(=O)\C=C\c2ccc(O)c(O)c2)[C@@H]1O)(OC(=O)\C=C\c1ccc(O)c(O)c1)C(O)=O
Relative Density.1.64 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 23 mg/mL (44.53 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9363 mL9.6815 mL19.3630 mL96.8148 mL
5 mM0.3873 mL1.9363 mL3.8726 mL19.3630 mL
10 mM0.1936 mL0.9681 mL1.9363 mL9.6815 mL
20 mM0.0968 mL0.4841 mL0.9681 mL4.8407 mL

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