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1-Decarboxy-3-oxo-ceanothic acid
Catalog No. TN2529Cas No. 214150-74-0
1-Decarboxy-3-oxo-ceanothic acid exhibits in vitro cytotoxic activity in a human ovarian adenocarcinoma cell line, mediated at least in part by induction of apoptosis. It is cytotoxic against OVCAR-3 and HeLa cancer cell lines with IC50 values of 2.8 and 6.6 microg/mL, respectively, and has an IC50 of 11.3 microg/mL against normal cell line FS-5.
1-Decarboxy-3-oxo-ceanothic acid
Catalog No. TN2529Cas No. 214150-74-0
1-Decarboxy-3-oxo-ceanothic acid exhibits in vitro cytotoxic activity in a human ovarian adenocarcinoma cell line, mediated at least in part by induction of apoptosis. It is cytotoxic against OVCAR-3 and HeLa cancer cell lines with IC50 values of 2.8 and 6.6 microg/mL, respectively, and has an IC50 of 11.3 microg/mL against normal cell line FS-5.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $740 | Backorder | |
| 1 mL x 10 mM (in DMSO) | $750 | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | 1-Decarboxy-3-oxo-ceanothic acid exhibits in vitro cytotoxic activity in a human ovarian adenocarcinoma cell line, mediated at least in part by induction of apoptosis. It is cytotoxic against OVCAR-3 and HeLa cancer cell lines with IC50 values of 2.8 and 6.6 microg/mL, respectively, and has an IC50 of 11.3 microg/mL against normal cell line FS-5. |
| Molecular Weight | 440.668 |
| Formula | C29H44O3 |
| Cas No. | 214150-74-0 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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