Powder: -20°C for 3 years | In solvent: -80°C for 1 year
2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP). 2'-Fluoro-2'-Deoxyadenosine showed good in vivo activity against tumors expressing E. coli PNP. 2'-Fluoro-2'-Deoxyadenosine can be used to synthesize 2'-deoxy-2'-fluoromodified oligonucleotides that can hybridize to RNA.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 mg | In stock | $ 41.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | 2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP). 2'-Fluoro-2'-Deoxyadenosine showed good in vivo activity against tumors expressing E. coli PNP. 2'-Fluoro-2'-Deoxyadenosine can be used to synthesize 2'-deoxy-2'-fluoromodified oligonucleotides that can hybridize to RNA. |
Molecular Weight | 269.23 |
Formula | C10H12FN5O3 |
CAS No. | 64183-27-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (185.71 mM)
You can also refer to dose conversion for different animals. More
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2'-Fluoro-2'-Deoxyadenosine 64183-27-3 Cell Cycle/Checkpoint DNA Damage/DNA Repair Nucleoside Antimetabolite/Analog tumor 2' Fluoro 2' Deoxyadenosine inhibit FAde purine nucleoside phosphorylase 2'Fluoro2'Deoxyadenosine Inhibitor oligonucleotide inhibitor