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2'-MeCCPA

Catalog No. T22489Cas No. 205171-12-6
Alias 2-Chloro-N-cyclopentyl-2′-C-methyladenosine

2'-MeCCPA is a potent and highly selective A1 adenosine receptor (A1AR) agonist with a K-value of 1.8 nM for AR. 2'-MeCCPA inhibits trichostatin-stimulated adenylate cyclase activity with an IC value of 13.1 nM, exhibits analgesic activity, and can be used in the study of HCV.

2'-MeCCPA

2'-MeCCPA

Purity: 99.93%
Catalog No. T22489Alias 2-Chloro-N-cyclopentyl-2′-C-methyladenosineCas No. 205171-12-6
2'-MeCCPA is a potent and highly selective A1 adenosine receptor (A1AR) agonist with a K-value of 1.8 nM for AR. 2'-MeCCPA inhibits trichostatin-stimulated adenylate cyclase activity with an IC value of 13.1 nM, exhibits analgesic activity, and can be used in the study of HCV.
Pack SizePriceAvailabilityQuantity
1 mg$40In Stock
5 mg$93In Stock
10 mg$179In Stock
25 mg$297In Stock
50 mg$453In Stock
100 mg$653In Stock
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Purity:99.93%
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Product Introduction

Bioactivity
Description
2'-MeCCPA is a potent and highly selective A1 adenosine receptor (A1AR) agonist with a K-value of 1.8 nM for AR. 2'-MeCCPA inhibits trichostatin-stimulated adenylate cyclase activity with an IC value of 13.1 nM, exhibits analgesic activity, and can be used in the study of HCV.
In vivo
During reperfusion, 2'-MeCCPA (1 nM-1 M) significantly reduces the infarct area and risk ratio in male Sprague-Dawley rats[2].
Alias2-Chloro-N-cyclopentyl-2′-C-methyladenosine
Chemical Properties
Molecular Weight383.83
FormulaC16H22ClN5O4
Cas No.205171-12-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (260.53 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6053 mL13.0266 mL26.0532 mL130.2660 mL
5 mM0.5211 mL2.6053 mL5.2106 mL26.0532 mL
10 mM0.2605 mL1.3027 mL2.6053 mL13.0266 mL
20 mM0.1303 mL0.6513 mL1.3027 mL6.5133 mL
50 mM0.0521 mL0.2605 mL0.5211 mL2.6053 mL
100 mM0.0261 mL0.1303 mL0.2605 mL1.3027 mL

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