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3-Epiursolic acid

🥰Excellent
Catalog No. TN1249Cas No. 989-30-0

3-Epiursolic acid may have antiinflammatory activity, it shows inhibition on Cathepsins L (catL), the IC50 value of 6.5 μM, cathepsins L (catL) and B play an important role in tumor progression and have been considered promising therapeutic targets in the development of novel anticancer agents.

3-Epiursolic acid

3-Epiursolic acid

🥰Excellent
Purity: 98.81%
Catalog No. TN1249Cas No. 989-30-0
3-Epiursolic acid may have antiinflammatory activity, it shows inhibition on Cathepsins L (catL), the IC50 value of 6.5 μM, cathepsins L (catL) and B play an important role in tumor progression and have been considered promising therapeutic targets in the development of novel anticancer agents.
Pack SizePriceAvailabilityQuantity
1 mg$48In Stock
5 mg$129In Stock
1 mL x 10 mM (in DMSO)$157In Stock
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Purity:98.81%
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Product Introduction

Bioactivity
Description
3-Epiursolic acid may have antiinflammatory activity, it shows inhibition on Cathepsins L (catL), the IC50 value of 6.5 μM, cathepsins L (catL) and B play an important role in tumor progression and have been considered promising therapeutic targets in the
Targets&IC50
Cathepsin L:6.5 μM (IC50), Cathepsin L:19.5 μM (Ki)
In vitro
All three extracts were found to exhibit antiinflammatory activity with the chloroform extract being the most active. Chemical investigations of petroleum ether and chloroform extracts led to the isolation of beta-sitosterol, ursolic acid, oleanolic acid, 3-Epiursolic acid, 3-epioleanolic acid, and minor triterpenoids of derivatives of ursolic acid and oleanolic acids. Chromatographic purification of the methanol extract yielded two iridoid glucosides, verbenalin and hastatoside, a phenylpropanoid glycoside, verbascoside and beta-sitosterol-D-glucoside.
Chemical Properties
Molecular Weight456.7
FormulaC30H48O3
Cas No.989-30-0
Smiles[H][C@@]12[C@@H](C)[C@H](C)CC[C@@]1(CC[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC[C@@H](O)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O
Relative Density.1.09 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 45 mg/mL (98.53 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1896 mL10.9481 mL21.8962 mL109.4811 mL
5 mM0.4379 mL2.1896 mL4.3792 mL21.8962 mL
10 mM0.2190 mL1.0948 mL2.1896 mL10.9481 mL
20 mM0.1095 mL0.5474 mL1.0948 mL5.4741 mL
50 mM0.0438 mL0.2190 mL0.4379 mL2.1896 mL

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