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4-Diethylaminobenzaldehyde

🥰Excellent
Catalog No. T10140Cas No. 120-21-8

4-Diethylaminobenzaldehyde, a reversible aldehyde dehydrogenase (ALDH) inhibitor (Ki: 4 nM for ALDH1), exhibits a potent anti-androgenic effect (IC50: 1.71 μM).

4-Diethylaminobenzaldehyde

4-Diethylaminobenzaldehyde

🥰Excellent
Purity: 99.60%
Catalog No. T10140Cas No. 120-21-8
4-Diethylaminobenzaldehyde, a reversible aldehyde dehydrogenase (ALDH) inhibitor (Ki: 4 nM for ALDH1), exhibits a potent anti-androgenic effect (IC50: 1.71 μM).
Pack SizePriceAvailabilityQuantity
100 mg$43In Stock
200 mg$61In Stock
500 mg$98In Stock
1 g$142In Stock
1 mL x 10 mM (in DMSO)$30In Stock
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Purity:99.60%
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Product Introduction

Bioactivity
Description
4-Diethylaminobenzaldehyde, a reversible aldehyde dehydrogenase (ALDH) inhibitor (Ki: 4 nM for ALDH1), exhibits a potent anti-androgenic effect (IC50: 1.71 μM).
In vitro
4-Diethylaminobenzaldehyde (DEAB) is a reversible competitive inhibitor of ALDH1, with a Ki of 4 nM (competitive with the aldehyde substrate), and it irreversibly inactivates ALDH7A1 by forming a stable, covalent acyl-enzyme species[1].
Chemical Properties
Molecular Weight177.24
FormulaC11H15NO
Cas No.120-21-8
SmilesCCN(CC)C1=CC=C(C=O)C=C1
Relative Density.1.029 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 10 mg/mL (56.42 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM5.6421 mL28.2103 mL56.4207 mL282.1034 mL
5 mM1.1284 mL5.6421 mL11.2841 mL56.4207 mL
10 mM0.5642 mL2.8210 mL5.6421 mL28.2103 mL
20 mM0.2821 mL1.4105 mL2.8210 mL14.1052 mL
50 mM0.1128 mL0.5642 mL1.1284 mL5.6421 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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