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7-Acetoxy-4-methylcoumarin
🥰Excellent
Catalog No. T7037Cas No. 2747-05-9
Alias MU-Ac
7-Acetoxy-4-methylcoumarin is a fluorescent substrate for carboxylesterases and acts as an inhibitor of GST, which can be isolated from Trigonella foenum graceum and inhibits AFB1-DNA binding.
7-Acetoxy-4-methylcoumarin
🥰Excellent
Catalog No. T7037Alias MU-AcCas No. 2747-05-9
7-Acetoxy-4-methylcoumarin is a fluorescent substrate for carboxylesterases and acts as an inhibitor of GST, which can be isolated from Trigonella foenum graceum and inhibits AFB1-DNA binding.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 200 mg | $29 | In Stock |
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | 7-Acetoxy-4-methylcoumarin is a fluorescent substrate for carboxylesterases and acts as an inhibitor of GST, which can be isolated from Trigonella foenum graceum and inhibits AFB1-DNA binding. |
| In vitro | METHODS: A pair of peptides with 18 amino acid residues spanning Lys201 (K201 peptide) and another with 20 residues containing Lys334 (K334 peptide) were synthesized and analyzed using high-performance LC-MS/MS to demonstrate the acetylation effect of 7-Acetoxy-4-methylcoumarin on both peptides. RESULTS 7-Acetoxy-4-methylcoumarin effectively acetylated Lys201 and Lys334 in each peptide, and the amount of acetylated peptide increased in a 7-Acetoxy-4-methylcoumarin dose-dependent manner. [1] |
| Alias | MU-Ac |
| Molecular Weight | 218.21 |
| Formula | C12H10O4 |
| Cas No. | 2747-05-9 |
| Smiles | CC(=O)Oc1ccc2c(C)cc(=O)oc2c1 |
| Relative Density. | 1.263g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 45 mg/mL (206.23 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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