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9-hydroxy Stearic Acid

9-hydroxy Stearic Acid
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Purity:99.7%
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9-hydroxy Stearic Acid

Catalog No. T37067Cas No. 3384-24-5
9-hydroxy Stearic Acid is a hydroxy fatty acid that is the active metabolite of 9-PAHSA. 9-hydroxy Stearic Acid is formed from 9-PAHSA through carboxyl ester lipase in the liver and pancreas. The 9-hydroxy Stearic Acid (5 μM) was stearic acid, which inhibited the expression of histone deacetylase 1 (HDAC1) in the lysate of HT-29 colon cancer cells. 3. When the concentration was 100 μM.1, the proliferation of HT-29 cells was inhibited and cell cycle arrest was induced in G0/ g1 phase.
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Pack SizePriceAvailabilityQuantity
1 mg$39In Stock
5 mg$172In Stock
10 mg$297In Stock
25 mg$492In Stock
50 mg$718In Stock
100 mg$987In Stock
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Product Introduction

Bioactivity
Description
9-hydroxy Stearic Acid is a hydroxy fatty acid that is the active metabolite of 9-PAHSA. 9-hydroxy Stearic Acid is formed from 9-PAHSA through carboxyl ester lipase in the liver and pancreas. The 9-hydroxy Stearic Acid (5 μM) was stearic acid, which inhibited the expression of histone deacetylase 1 (HDAC1) in the lysate of HT-29 colon cancer cells. 3. When the concentration was 100 μM.1, the proliferation of HT-29 cells was inhibited and cell cycle arrest was induced in G0/ g1 phase.
In vitro
9-hydroxy Stearic acid is a hydroxy fatty acid and an active metabolite of 9-PAHSA .[1][2]
It is formed from 9-PAHSA by liver and pancreatic carboxyl ester lipases.2 9-hydroxy Stearic acid (5 µM) inhibits histone deacetylase 1 (HDAC1) in HT-29 colon cancer cell lysates.[3]
It inhibits the proliferation of, and induces cell cycle arrest at the G0/G1 phase in, HT-29 cells when used at a concentration of 100 µM.1.[1]
Chemical Properties
Molecular Weight300.48
FormulaC18H36O3
Cas No.3384-24-5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 60 mg/mL (199.68 mM)
Chloroform: Soluble
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3280 mL16.6400 mL33.2801 mL166.4004 mL
5 mM0.6656 mL3.3280 mL6.6560 mL33.2801 mL
10 mM0.3328 mL1.6640 mL3.3280 mL16.6400 mL
20 mM0.1664 mL0.8320 mL1.6640 mL8.3200 mL
50 mM0.0666 mL0.3328 mL0.6656 mL3.3280 mL
100 mM0.0333 mL0.1664 mL0.3328 mL1.6640 mL

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