Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ABT-670 is a selective agonist of dopamine D4 receptor. For human D4, ferret D4, and rat D4, the EC50 values are 89 nM, 160 nM, and 93 nM , respectively.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | ABT-670 is a selective agonist of dopamine D4 receptor. For human D4, ferret D4, and rat D4, the EC50 values are 89 nM, 160 nM, and 93 nM , respectively. |
Targets&IC50 | D4 (Ferret):160 nM(EC50), D4 (human):(EC50)89 nM, D4 (rat):93 nM(EC50) |
In vitro | ABT-670 is a selective D4 agonist. For human?D4, ferret?D4, and rat?D4, the EC50s values are 89 nM, 160 nM, and 93 nM, respectively[1]. |
In vivo | ABT-670 (0.1 μmol/kg) robustly induces a high (75%) incidence of erections in male rats. ABT-670 exhibits excellent oral bioavailability in rat, dog, and monkey (68%, 85%, and 91%, respectively) with comparable efficacy, safety, and tolerability[1]. |
Molecular Weight | 325.4 |
Formula | C19H23N3O2 |
CAS No. | 630119-43-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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ABT-670 630119-43-6 GPCR/G Protein Neuroscience Dopamine Receptor ABT670 ABT 670 inhibitor inhibit