Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AZD5904 is a potent and irreversible inhibitor of human Myeloperoxidase (MPO, IC50: 140 nM) which has similar potency in mouse and rat.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 48.00 | |
2 mg | In stock | $ 68.00 | |
5 mg | In stock | $ 113.00 | |
10 mg | In stock | $ 155.00 | |
25 mg | In stock | $ 313.00 | |
50 mg | In stock | $ 563.00 | |
100 mg | In stock | $ 812.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 125.00 |
Description | AZD5904 is a potent and irreversible inhibitor of human Myeloperoxidase (MPO, IC50: 140 nM) which has similar potency in mouse and rat. |
Targets&IC50 | MPO (human):140 nM |
In vitro | In isolated human neutrophils, 1 μM AZD5904 inhibits PMA stimulated HOCl by >90%[1]. It is 10 to 19-fold selective compare to the closely related lactoperoxidase and thyroid peroxidase. For a broad panel of other enzymes, ion channels, and receptors, is higher than >70-fold. |
Molecular Weight | 252.29 |
Formula | C10H12N4O2S |
CAS No. | 618913-30-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 65 mg/mL (257.64 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
AZD5904 618913-30-7 Metabolism Glutathione Peroxidase AZD 5904 Inhibitor inhibit AZD-5904 inhibitor