Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AnaMorelin hydrochloride (RC-1291 hydrochloride) is a novel ghrelin receptor agonist(EC50 : 0.74 nM, in the FLIPR assay).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 30.00 | |
2 mg | In stock | $ 43.00 | |
5 mg | In stock | $ 67.00 | |
10 mg | In stock | $ 97.00 | |
25 mg | In stock | $ 148.00 | |
50 mg | In stock | $ 187.00 | |
100 mg | In stock | $ 247.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 87.00 |
Description | AnaMorelin hydrochloride (RC-1291 hydrochloride) is a novel ghrelin receptor agonist(EC50 : 0.74 nM, in the FLIPR assay). |
Targets&IC50 | ghrelin receptor(in the FLIPR assay):0.74 nM(EC50) |
In vivo | In rats, AnaMorelin hydrochloride(ANAM) significantly and dose-dependently increased FI and BW at all dose levels compared with control, and significantly increased GH levels at 10 or 30 mg/kg doses. Increases in GH and IGF-1 levels were observed following ANAM administration in pigs[1]. |
Animal Research | Fluorescent imaging plate reader and binding assays in HEK293 and baby hamster kidney cells determined the agonist and antagonist activity of ANAM, and its affinity for the ghrelin receptor. Rat pituitary cells were incubated with ANAM to evaluate its effect on growth hormone (GH) release. In vivo, rats were treated with ANAM 3, 10, or 30 mg/kg, or control orally, once daily for 6 days to evaluate the effect on food intake (FI) and body weight (BW), and once to assess GH response. In pigs, single (3.5 mg/kg) or continuous (1 mg/kg/day) ANAM doses were administered to assess GH and insulin-like growth factor (IGF-1) response[1]. |
Synonyms | RC-1291 hydrochloride, ONO-7643 hydrochloride |
Molecular Weight | 583.16 |
Formula | C31H43ClN6O3 |
CAS No. | 861998-00-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 28 mg/mL (48.01 mM)
You can also refer to dose conversion for different animals. More
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AnaMorelin hydrochloride 861998-00-7 GPCR/G Protein GHSR RC 1291 Hydrochloride Inhibitor RC1291 Hydrochloride RC-1291 hydrochloride inhibit ONO7643 Hydrochloride ONO-7643 ONO 7643 RC-1291 Growth hormone secretagogue receptor ONO-7643 hydrochloride ONO7643 ONO 7643 Hydrochloride AnaMorelin Hydrochloride Anamorelin RC-1291 Hydrochloride RC1291 ONO-7643 Hydrochloride RC 1291 inhibitor