keep away from direct sunlight,store under nitrogen
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Arbutamine (GP 21213) is a novel potent non-selective beta-adrenoceptor agonist with alpha-1-sympathomimetic activity.Arbutamine promotes cardiac stress and increases heart rate, cardiac contractility.Arbutamine can be used to study cardiac stress and coronary artery disease
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 397.00 | |
5 mg | In stock | $ 970.00 | |
10 mg | In stock | $ 1,180.00 | |
25 mg | In stock | $ 1,580.00 | |
50 mg | In stock | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | Arbutamine (GP 21213) is a novel potent non-selective beta-adrenoceptor agonist with alpha-1-sympathomimetic activity.Arbutamine promotes cardiac stress and increases heart rate, cardiac contractility.Arbutamine can be used to study cardiac stress and coronary artery disease |
In vitro | The affinity constants (Ka) of arbutamine and isoproterenol for cardiac beta1-adrenergic receptors, as determined by competition binding assays, were found to be 7.32 and 6.04, respectively[3]. |
In vivo | In the electrical stimulation of the left atrium of rats, Arbutamine increases contractility. The pD2 values (logarithm of the dose producing 50% of the maximum response) for Arbutamine and isoproterenol are 8.45 +/- 0.15 and 8.55 +/- 0.02, respectively. In the guinea pig trachea, Arbutamine and isoproterenol induced a concentration-dependent relaxation, which was inhibited by propranolol[3]. |
Synonyms | GP 21213 |
Molecular Weight | 317.38 |
Formula | C18H23NO4 |
CAS No. | 128470-16-6 |
keep away from direct sunlight,store under nitrogen
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Arbutamine 128470-16-6 GPCR/G Protein Neuroscience Adrenergic Receptor GP 21213 inhibitor inhibit