Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BRD 9757 (N-Hydroxy-1-cyclopentene-1-carboxamide) is a selective inhibitor of HDAC6 (IC50 = 30 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 97.00 | |
5 mg | In stock | $ 239.00 | |
10 mg | In stock | $ 336.00 | |
25 mg | In stock | $ 536.00 | |
50 mg | In stock | $ 773.00 | |
100 mg | In stock | $ 1,080.00 | |
500 mg | In stock | $ 2,170.00 |
Description | BRD 9757 (N-Hydroxy-1-cyclopentene-1-carboxamide) is a selective inhibitor of HDAC6 (IC50 = 30 nM). |
In vitro | The IC50s are 0.638 μM, 1.79 μM, 0.694 μM, 21.80 μM, 18.32 μM, 12.61 μM, 1.09 μM and >33.33 μM, respectively for HDAC1, HDAC2, HDAC3, HDAC4, HDAC5, HDAC7, HDAC8 and HDAC9. BRD 9757 (10-30 μM) selectively increases Ac-tubulin levels without affecting histone acetylation[1]. |
Synonyms | BRD9757, N-Hydroxy-1-cyclopentene-1-carboxamide, BRD-9757 |
Molecular Weight | 127.14 |
Formula | C6H9NO2 |
CAS No. | 1423058-85-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: < 1.27 mg/mL (10 mM, insoluble or slightly soluble)
You can also refer to dose conversion for different animals. More
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BRD 9757 1423058-85-8 Chromatin/Epigenetic DNA Damage/DNA Repair HDAC BRD9757 N-Hydroxy-1-cyclopentene-1-carboxamide BRD-9757 inhibitor inhibit