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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $34 | In Stock | |
10 mg | $61 | In Stock | |
25 mg | $141 | In Stock | |
50 mg | $265 | In Stock | |
100 mg | $382 | In Stock | |
200 mg | $536 | In Stock | |
1 mL x 10 mM (in DMSO) | $37 | In Stock |
Description | Balicatib (AAE581) is a potent and selective inhibitor of cathepsin K, used in trials studying the treatment of osteoporosis. |
Kinase Assay | Cell-free kinase activity assays: Glutathione-S-transferase (GST)-tagged JAK kinase domains expressed in insect cells are purified before use in a peptide substrate phosphorylation assay. Assays are carried out in 384-well optiplates using an Alphascreen Protein Tyrosine Kinase P100 detection kit and a PerkinElmer Fusion Alpha instrument. |
Alias | AAE581 |
Molecular Weight | 411.54 |
Formula | C23H33N5O2 |
Cas No. | 354813-19-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 50 mg/mL (121.49 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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