Powder: -20°C for 3 years | In solvent: -80°C for 1 year
C-176 (STING inhibitor 1) is a strong, covalent mouse STING inhibitor
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | In stock | $ 39.00 | |
25 mg | In stock | $ 79.00 | |
50 mg | In stock | $ 137.00 | |
100 mg | In stock | $ 247.00 | |
200 mg | In stock | $ 367.00 | |
500 mg | In stock | $ 596.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 43.00 |
Description | C-176 (STING inhibitor 1) is a strong, covalent mouse STING inhibitor |
In vitro | C-176 significantly reduces STING-mediated, but not RIG-I- or TBK1-mediated, IFNβ reporter activity. Pretreatment with C-176 markedly reduces the CMA-mediated induction of serum levels of type I IFNs and IL-6. |
In vivo | C-176 strongly reduces STING-mediated, but not RIG-I- or TBK1-mediated, IFNβ reporter activity. Pretreatment with C-176 markedly reduce the CMA-mediated induction of serum levels of type I IFNs and IL-6. |
Synonyms | C176, STING inhibitor 1 |
Molecular Weight | 358.09 |
Formula | C11H7IN2O4 |
CAS No. | 314054-00-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL
You can also refer to dose conversion for different animals. More
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C-176 314054-00-7 Immunology/Inflammation STING C 176 Stimulator of Interferon Genes inhibit MPYS C176 ERIS STING inhibitor 1 TMEM173 Inhibitor MITA inhibitor