Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CCR6 inhibitor 1 is an effective and selective inhibitor of CCR6 (IC50 of monkey and human CCR6 was 0.45 nM and 6 nM, respectively). CCR6 is associated with both autoimmune and non-autoimmune diseases, so CCR6 inhibitor 1 is useful for in vitro and in vivo pathophysiology studies as a small molecule inhibitor of CCR6.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 148.00 | |
5 mg | In stock | $ 372.00 | |
10 mg | In stock | $ 556.00 | |
25 mg | In stock | $ 896.00 | |
50 mg | In stock | $ 1,220.00 | |
100 mg | In stock | $ 1,650.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 413.00 |
Description | CCR6 inhibitor 1 is an effective and selective inhibitor of CCR6 (IC50 of monkey and human CCR6 was 0.45 nM and 6 nM, respectively). CCR6 is associated with both autoimmune and non-autoimmune diseases, so CCR6 inhibitor 1 is useful for in vitro and in vivo pathophysiology studies as a small molecule inhibitor of CCR6. |
Targets&IC50 | CCR6 (monkey):0.45 nM, CCR7 (human):9400 nM, CCR6 (human):6 nM |
In vitro | CCR6 inhibitor 1 in human CCR6-transfected CHO cells showed a good correlation between Gi signal inhibitory activity and cell migration inhibitory activity, which could effectively inhibit CCR6-dependent cell migration and ERK phosphorylation increase in human primary cells[1]. |
Molecular Weight | 504.52 |
Formula | C24H23F3N4O3S |
CAS No. | 2437547-04-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 112.5 mg/mL (223.0 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
CCR6 inhibitor 1 2437547-04-9 Immunology/Inflammation Microbiology/Virology CCR CCR-6 inhibitor 1 inhibitor inhibit