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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $50 | In Stock | |
5 mg | $97 | In Stock | |
10 mg | $141 | In Stock | |
25 mg | $229 | In Stock | |
50 mg | $336 | In Stock | |
100 mg | $496 | In Stock | |
1 mL x 10 mM (in DMSO) | $126 | In Stock |
Description | CM-579 is a dual inhibitor of G9a and DNMT( IC50:16 nM, 32 nM for G9a and DNMT). It has potent in vitro cellular activity in a wide range of cancer cells. |
In vitro | CM-579 inhibits DNMT3A and DNMT3B ( IC50s: 92 nM and 1000 nM). The Kd of CM-579 for DNMT1 is 1.5 nM. [1] |
Molecular Weight | 492.65 |
Formula | C29H40N4O3 |
Cas No. | 1846570-40-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 45 mg/mL (91.34 mM) ![]() | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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