Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CU-CPT17e is a potent agonist of TLR(TLR3, TLR8, and TLR9).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 213.00 | |
5 mg | In stock | $ 441.00 | |
10 mg | In stock | $ 649.00 | |
25 mg | In stock | $ 987.00 | |
50 mg | In stock | $ 1,390.00 | |
100 mg | In stock | $ 1,870.00 |
Description | CU-CPT17e is a potent agonist of TLR(TLR3, TLR8, and TLR9). |
In vitro | The first small molecule 17e (CU-CPT17e) capable of simultaneously activating TLRs 3, 8, and 9. Biochemical studies demonstrated that 17e could induce a strong immune response via the production of various cytokines in human monocytic THP-1 cells. Furthermore, 17e inhibited the proliferation of HeLa cancer cells by triggering apoptosis and arresting the cell cycle at the S phase. These results showcase potential therapeutic applications of 17e in both vaccine adjuvants and anticancer therapies based on multi-TLR activation. |
Molecular Weight | 504.49 |
Formula | C27H24N2O8 |
CAS No. | 2109805-75-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 2 mg/mL (3.96 mM), Sonification is recommended
You can also refer to dose conversion for different animals. More
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CU-CPT17e 2109805-75-4 Immunology/Inflammation TLR Toll-like Receptor (TLR) CU CPT17e CUCPT17e Inhibitor CU-CPT-17e inhibit inhibitor