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Chlorhexidine dihydrochloride

Catalog No. T1147   CAS 3697-42-5
Synonyms: Chlorhexidine hydrochloride, Chlorhexidine 2HCl, NSC-185

Chlorhexidine dihydrochloride (NSC-185) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.

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Chlorhexidine dihydrochloride Chemical Structure
Chlorhexidine dihydrochloride, CAS 3697-42-5
Pack Size Availability Price/USD Quantity
100 mg In stock $ 39.00
500 mg In stock $ 89.00
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Purity: 99.39%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Chlorhexidine dihydrochloride (NSC-185) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.
In vitro Chlorhexidine is a chemical antiseptic.It is effective on both Gram-positive and Gram-negative bacteria, although it is less effective with some Gram-negative bacteria.It has both bactericidal and bacteriostatic mechanisms of action, the mechanism of action being membrane disruption, not ATPase inactivation as previously thought.It is also useful against fungi and enveloped viruses, though this has not been extensively investigated. Chlorhexidine is harmful in high concentrations, but is used safely in low concentrations in many products, such as mouthwash and contact lens solutions.
Synonyms Chlorhexidine hydrochloride, Chlorhexidine 2HCl, NSC-185
Molecular Weight 578.38
Formula C22H32Cl4N10
CAS No. 3697-42-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

DMSO: 93 mg/mL (160.8 mM)

TargetMolReferences and Literature

1. Jenkins S, et al. J Clin Periodontol, 1988, 15(7), 415-424. 2. Maki DG, et al. Lancet, 1991, 338(8763), 339-343.

TargetMolCitations

1. Sanders D W, Jumper C C, Ackerman P J, et al. SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation. Elife. 2021, 10: e65962.

Related compound libraries

This product is contained In the following compound libraries:
Drug Repurposing Compound Library Anti-Infection Compound Library Antibiotics Library Nonsteroidal Anti-Inflammatory Compound Library Bioactive Compound Library FDA-Approved & Pharmacopeia Drug Library Approved Drug Library Anti-Viral Compound Library Bioactive Compounds Library Max Immunology/Inflammation Compound Library

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Keywords

Chlorhexidine dihydrochloride 3697-42-5 Immunology/Inflammation Microbiology/Virology oxidation-reduction CAT Cell wall Antibacterial Antibiotic Antifection Chlorhexidine hydrochloride Inhibitor Chlorhexidine NSC 185 Chlorhexidine Hydrochloride Bacterial inhibit Chlorhexidine 2HCl NSC185 NSC-185 Chlorhexidine Dihydrochloride inhibitor

 

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