Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DHODH-IN-1 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 25 nM. DHODH-IN-1 is an inhibitor of the pyrimidine biosynthetic pathway.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 195.00 | |
2 mg | In stock | $ 293.00 | |
5 mg | In stock | $ 449.00 | |
10 mg | In stock | $ 659.00 | |
25 mg | In stock | $ 987.00 | |
50 mg | In stock | $ 1,390.00 | |
100 mg | In stock | $ 1,880.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 491.00 |
Description | DHODH-IN-1 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 25 nM. DHODH-IN-1 is an inhibitor of the pyrimidine biosynthetic pathway. |
Targets&IC50 | DHODH:25 nM |
In vitro | DHODH-IN-1 (4-100 nM) prevents the measles virus from replicating in cells. When transfecting cells with ssRNA molecules, DHODH-IN-1 (0.008-5 μM) can increase the expression of ISRE luciferase reporter gene. DHODH-IN-1 inhibits Jurkat cell proliferation with an IC50 value of 0.02 μM[1]. |
In vivo | The t1/2 for DHODH-IN-1 is 27–41 min[1]. |
Molecular Weight | 403.4 |
Formula | C21H20F3N3O2 |
CAS No. | 1800296-63-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (136.34 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
DHODH-IN-1 1800296-63-2 Metabolism Dehydrogenase DHODHIN1 DHODH IN 1 inhibitor inhibit