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Daltroban

Daltroban
Daltroban (SKF 96148) is a specific thromboxane A2 (TXA2) receptor antagonist. Daltroban shows protective effect in reperfusion injury. Daltroban increase intracellular calcium in vascular smooth muscle cells.
Catalog No. T15049Cas No. 79094-20-5
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Purity:99.49%
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Daltroban

Catalog No. T15049Cas No. 79094-20-5
Daltroban (SKF 96148) is a specific thromboxane A2 (TXA2) receptor antagonist. Daltroban shows protective effect in reperfusion injury. Daltroban increase intracellular calcium in vascular smooth muscle cells.
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Pack SizePriceAvailabilityQuantity
1 mg$89In Stock
5 mg$219In Stock
10 mg$326In Stock
25 mg$546In Stock
50 mg$778In Stock
100 mg$1,060In Stock
1 mL x 10 mM (in DMSO)$198In Stock
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Product Introduction

Bioactivity
Description
Daltroban (SKF 96148) is a specific thromboxane A2 (TXA2) receptor antagonist. Daltroban shows protective effect in reperfusion injury. Daltroban increase intracellular calcium in vascular smooth muscle cells.
In vivo
Daltroban (20 mg/kg per hour i.v.) reduces the ischaemia-induced rise in the ST segment and prevented the development of a Q-wave in the ECG during reperfusion, in comparison with vehicle (physiological saline)-treated cats. Daltroban (1 mg/kg; i.v.; per hour) exerts protective effect in reperfusion injury following acute myocardial ischemia in cats[2]. Daltroban protects the myocardium from ischaemic injury and that this effect involves prevention of ischaemia-induced leukocytosis[3].
AliasBM-13505, SKF 96148
Chemical Properties
Molecular Weight353.82
FormulaC16H16ClNO4S
Cas No.79094-20-5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (141.31 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.8263 mL14.1315 mL28.2630 mL141.3148 mL
5 mM0.5653 mL2.8263 mL5.6526 mL28.2630 mL
10 mM0.2826 mL1.4131 mL2.8263 mL14.1315 mL
20 mM0.1413 mL0.7066 mL1.4131 mL7.0657 mL
50 mM0.0565 mL0.2826 mL0.5653 mL2.8263 mL
100 mM0.0283 mL0.1413 mL0.2826 mL1.4131 mL

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