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Daltroban

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Purity:99.49%

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COA HNMR LCMS HPLC

Daltroban

Catalog No. T15049Cas No. 79094-20-5

Daltroban (SKF 96148) is a specific thromboxane A2 (TXA2) receptor antagonist. Daltroban shows protective effect in reperfusion injury. Daltroban increase intracellular calcium in vascular smooth muscle cells.

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Pack Size	Price	Availability
1 mg	$97	In Stock
5 mg	$262	In Stock
10 mg	$389	In Stock
25 mg	$592	In Stock
50 mg	$834	In Stock
100 mg	$1,120	In Stock
500 mg	$2,250	In Stock
1 mL x 10 mM (in DMSO)	$198	In Stock

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Product Introduction

Bioactivity

Description	Daltroban (SKF 96148) is a specific thromboxane A2 (TXA2) receptor antagonist. Daltroban shows protective effect in reperfusion injury. Daltroban increase intracellular calcium in vascular smooth muscle cells.
In vivo	Daltroban (20 mg/kg per hour i.v.) reduces the ischaemia-induced rise in the ST segment and prevented the development of a Q-wave in the ECG during reperfusion, in comparison with vehicle (physiological saline)-treated cats. Daltroban (1 mg/kg; i.v.; per hour) exerts protective effect in reperfusion injury following acute myocardial ischemia in cats[2]. Daltroban protects the myocardium from ischaemic injury and that this effect involves prevention of ischaemia-induced leukocytosis[3].
Alias	BM-13505, SKF 96148

Chemical Properties

Molecular Weight	353.82
Formula	C16H16ClNO4S
Cas No.	79094-20-5

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (141.31 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8263 mL	14.1315 mL	28.2630 mL	141.3148 mL
5 mM	0.5653 mL	2.8263 mL	5.6526 mL	28.2630 mL
10 mM	0.2826 mL	1.4131 mL	2.8263 mL	14.1315 mL
20 mM	0.1413 mL	0.7066 mL	1.4131 mL	7.0657 mL
50 mM	0.0565 mL	0.2826 mL	0.5653 mL	2.8263 mL
100 mM	0.0283 mL	0.1413 mL	0.2826 mL	1.4131 mL

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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

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