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Doxepin hydrochloride

Catalog No. T1540 CAS 1229-29-4

Synonyms: Inhibitor, Doxepin, inhibit, Histamine Receptor, Sinequan, Doxepin hydrochloride, Cytochrome P450, Doxepin HCl, antidepressant, Novoxapin, Toruan, CYPs, Quitaxon, Aponal

Doxepin Hydrochloride is a dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.

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Doxepin hydrochloride, CAS 1229-29-4

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Inhibitor, Doxepin, inhibit, Histamine Receptor, Sinequan, Doxepin hydrochloride, Cytochrome P450, Doxepin HCl, antidepressant, Novoxapin, Toruan, CYPs, Quitaxon, Aponal
Molecular Weight	315.84
Formula	C19H22ClNO
CAS No.	1229-29-4

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 31.6 mg/mL(100 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature

1. Ehlert FJ, et al. J Pharmacol Exp Ther. 1990 Apr;253(1):13-9.

Related compound libraries

This product is contained In the following compound libraries：

GPCR Compound Library Anti-Cardiovascular Disease Compound Library Serotonin Receptor-Targeted Compound Library Histamine & Melatonin Receptor-Targeted Compound Library Neurotransmitter Receptor Compound Library Endocrinology-Hormone Compound Library Anti-Parkinson's Disease Compound Library Inhibitor Library Drug-induced Liver Injury (DILI) Compound Library Immunology/Inflammation Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.