store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Eupatolide is isolated from the flowers of Inula japonica with anti-inflammatory activity. Eupatolide can be used in studies about TRAIL resistance in breast cancer cells.
Pack Size | Availability | Price/USD | Quantity |
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1 mg | Inquiry | $ 297.00 |
Description | Eupatolide is isolated from the flowers of Inula japonica with anti-inflammatory activity. Eupatolide can be used in studies about TRAIL resistance in breast cancer cells. |
In vitro | Eupatolide exhibits potent cytotoxicity against HL-60, SMMC-7721, A-549, MCF-7, and SW-480 cancer cell lines (IC50: 1.57 to 22.58 uM). Eupatolide sensitizes breast cancer cells to TRAIL through the down-regulation of c-FLIP expression. In RAW264.7 cells, Eupatolide inhibits lipopolysaccharide-induced COX-2 and iNOS expression by inducing proteasomal degradation of TRAF6. Eupatolide suppresses PDGF-induced proliferation and migration of VSMC through HO-1 induction via ROS-Nrf2 pathway and may be a potential HO-1 inducer for preventing or treating vascular diseases[1]. |
Molecular Weight | 248.32 |
Formula | C15H20O3 |
CAS No. | 6750-25-0 |
store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Eupatolide 6750-25-0 Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Cytoskeletal Signaling DNA Damage/DNA Repair GPCR/G Protein Immunology/Inflammation MAPK Neuroscience NF-Κb PI3K/Akt/mTOR signaling Tyrosine Kinase/Adaptors TNF NOS NF-κB COX Akt ROS Nrf2 DNA/RNA Synthesis NO Synthase PDGFR Prostaglandin Receptor inhibitor inhibit