Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Fluspirilene (R 6218) is a non-competitive L-type calcium channel antagonist (IC50: 0.03 μM).Fluspirilene is a long-acting antipsychotic compound used in the treatment of schizophrenia.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 44.00 | |
5 mg | In stock | $ 98.00 | |
10 mg | In stock | $ 155.00 | |
25 mg | In stock | $ 262.00 | |
50 mg | In stock | $ 389.00 | |
100 mg | In stock | $ 573.00 | |
500 mg | In stock | $ 1,190.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 108.00 |
Description | Fluspirilene (R 6218) is a non-competitive L-type calcium channel antagonist (IC50: 0.03 μM).Fluspirilene is a long-acting antipsychotic compound used in the treatment of schizophrenia. |
Targets&IC50 | L-type calcium channel:0.03 μM |
In vitro |
Fluspirilene (1.25, 2.5, and 5 μM) demonstrates the inhibition of proliferation of T98, U87, and all GSC lines, while Fluspirilene (2.5 and 5 μM) inhibits the proliferation of U251 and SNB19.[2] Fluspirilene decreases the viability and suppresses the sphere-forming of glioma stem cell lines in a dose-dependent manner.[2] |
In vivo | Fluspirilene obviously prolongs the survival of the TGS04 mouse model. Mice treated with fluspirilene display a remarkable reduction in tumor size.[2] |
Synonyms | Redeptin, R 6218 |
Molecular Weight | 475.57 |
Formula | C29H31F2N3O |
CAS No. | 1841-19-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30 mg/mL (63.08 mM), ultrasonic and warming and heat to 60°C
You can also refer to dose conversion for different animals. More
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Fluspirilene 1841-19-6 Membrane transporter/Ion channel Metabolism Calcium Channel Redeptin R6218 R 6218 R-6218 inhibitor inhibit