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Furanodienone

Catalog No. T4S0544 CAS 24268-41-5

Purity 98.00% Datasheet

1. Furanodienone has effects on MCF-7 cells are mediated, at least in part, by inhibiting ERα signaling. 2. Furanodienone inhibits EGFR/HER2 signaling pathway in BT474 and SKBR3 cells, the effect is specifically dependent on the expression of HER2 but not EGFR .

Furanodienone, CAS 24268-41-5

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5 mg	Inquiry	180.00

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Purity 98.00%

HNMR COA Datasheet MSDS

Biological Description

Chemical Properties

Storage & Solubility Information

Description	1. Furanodienone has effects on MCF-7 cells are mediated, at least in part, by inhibiting ERα signaling. 2. Furanodienone inhibits EGFR/HER2 signaling pathway in BT474 and SKBR3 cells, the effect is specifically dependent on the expression of HER2 but not EGFR .
Targets&IC50

Molecular Weight	230.3
Formula	C15H18O2
CAS No.	24268-41-5

Storage

-20℃ 3 years powder

-80℃ 2 years in solvent

Solubility Information

Chloroform: Soluble

Dichloromethane: Soluble

Ethyl Acetate: Soluble

Acetone: Soluble

DMSO: Soluble

Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature

1. Li Y W , Zhu G Y , Shen X L , et al. Furanodienone induces cell cycle arrest and apoptosis by suppressing EGFR/HER2 signaling in HER2-overexpressing human breast cancer cells[J]. Cancer Chemother Pharmacol, 2011, 68(5):1315-1323.

Related compound libraries

This product is contained In the following compound libraries：

Bioactive Compound Library Selected Plant-sourced Compound Library

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Answers to questions you may have can be found in the Inhibitor Handling Instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

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