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Furanodienone

Furanodienone
1. Furanodienone has effects on MCF-7 cells are mediated, at least in part, by inhibiting ERα signaling. 2. Furanodienone inhibits EGFR/HER2 signaling pathway in BT474 and SKBR3 cells, the effect is specifically dependent on the expression of HER2 but not EGFR .
Catalog No. T4S0544Cas No. 24268-41-5
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Purity:98.32%
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Furanodienone

Catalog No. T4S0544Cas No. 24268-41-5
1. Furanodienone has effects on MCF-7 cells are mediated, at least in part, by inhibiting ERα signaling. 2. Furanodienone inhibits EGFR/HER2 signaling pathway in BT474 and SKBR3 cells, the effect is specifically dependent on the expression of HER2 but not EGFR .
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Pack SizePriceAvailabilityQuantity
1 mg$54In Stock
5 mg$122In Stock
10 mg$178In Stock
25 mg$297In Stock
50 mg$449In Stock
1 mL x 10 mM (in DMSO)$115In Stock
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Product Introduction

Bioactivity
Description
1. Furanodienone has effects on MCF-7 cells are mediated, at least in part, by inhibiting ERα signaling. 2. Furanodienone inhibits EGFR/HER2 signaling pathway in BT474 and SKBR3 cells, the effect is specifically dependent on the expression of HER2 but not EGFR .
Chemical Properties
Molecular Weight230.3
FormulaC15H18O2
Cas No.24268-41-5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble
DMSO: 22.5 mg/mL (97.7 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.3422 mL21.7108 mL43.4216 mL217.1081 mL
5 mM0.8684 mL4.3422 mL8.6843 mL43.4216 mL
10 mM0.4342 mL2.1711 mL4.3422 mL21.7108 mL
20 mM0.2171 mL1.0855 mL2.1711 mL10.8554 mL
50 mM0.0868 mL0.4342 mL0.8684 mL4.3422 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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