Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GLPG0634 analog (GLPG0634 analogue) is a specific JAK1 inhibitor with IC50 of 10/28/810/116 nM for JAK1/2/3 and TYK2, respectively.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 34.00 | |
2 mg | In stock | $ 48.00 | |
5 mg | In stock | $ 80.00 | |
10 mg | In stock | $ 147.00 | |
25 mg | In stock | $ 277.00 | |
50 mg | In stock | $ 490.00 | |
100 mg | In stock | $ 693.00 | |
500 mg | In stock | $ 1,450.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 89.00 |
Description | GLPG0634 analog (GLPG0634 analogue) is a specific JAK1 inhibitor with IC50 of 10/28/810/116 nM for JAK1/2/3 and TYK2, respectively. |
Targets&IC50 | JAK2:28nM, JAK1:10nM, TYK2:116 nM, JAK3:810nM |
Kinase Assay | EC50 values of the test compounds are calculated from serial dilution series ranging from 200 to 0.1 μM. Cells are seeded in 96-well plates at a density of 5,000 cells per well in 100 μL medium. The next day, 100 μL medium containing each test compound is added. Cells are incubated for 16 h, fixed and processed for automated microscopy. EC50 estimates are calculated using four-parameter log-logistic fit with the package drc[1]. |
Synonyms | GLPG0634 analogue |
Molecular Weight | 410.43 |
Formula | C23H18N6O2 |
CAS No. | 1206101-20-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 199.8 mM
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
GLPG0634 analog 1206101-20-3 Angiogenesis Chromatin/Epigenetic JAK/STAT signaling Stem Cells Tyrosine Kinase/Adaptors JAK Tyrosine Kinases GLPG0634 Inhibitor AK-STAT GLPG-0634 GLPG0634 analogue Janus kinase inhibit Hela cell GLPG 0634 GLPG-0634 analog OSM/IL-lβ inhibitor