Powder: -20°C for 3 years
In solvent: -80°C for 2 years
GR 113808 displays 300-fold selectivity over 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2C and 5-HT3 receptors. GR 113808 is a potent and highly selective antagonist of 5-HT4 receptor (pKb= 8.8).
Description | GR 113808 displays 300-fold selectivity over 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2C and 5-HT3 receptors. GR 113808 is a potent and highly selective antagonist of 5-HT4 receptor (pKb= 8.8). |
In vivo | GR113808 (i.p.; 1 mg/kg; 5-7 days starting 24 h after induction of colitis) displays a obviously enhance in the disease activity index which includes evaluation of weight loss, stool consistency, and presence of fecal blood [2]. |
Molecular Weight | 393.5 |
Formula | C19H27N3O4S |
CAS No. | 144625-51-4 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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GR 113808 144625-51-4 G蛋白偶联受体 神经科学 5-HT Receptor Inhibitor inhibitor inhibit