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HBDDE
🥰Excellent
Catalog No. T39030Cas No. 154675-18-0
HBDDE is a selective model inhibitor of the isoenzymes PKCα and PKCγ with IC 50 s of 43 μM and 50 μM, respectively.HBDDE has a higher affinity for PKCα/PKCγ than the PKCδ, PKCβI, and PKCβII isoenzymes.HBDDE is a derivative of ellagic acid, which induces apoptosis in neuronal cells. HBDDE is a derivative of ellagic acid and induces apoptosis in neuronal cells.
HBDDE
🥰Excellent
Purity: 98.02%
Catalog No. T39030Cas No. 154675-18-0
HBDDE is a selective model inhibitor of the isoenzymes PKCα and PKCγ with IC 50 s of 43 μM and 50 μM, respectively.HBDDE has a higher affinity for PKCα/PKCγ than the PKCδ, PKCβI, and PKCβII isoenzymes.HBDDE is a derivative of ellagic acid, which induces apoptosis in neuronal cells. HBDDE is a derivative of ellagic acid and induces apoptosis in neuronal cells.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $297 | In Stock | |
| 5 mg | $728 | In Stock | |
| 10 mg | $993 | In Stock | |
| 25 mg | $1,470 | In Stock | |
| 50 mg | $1,980 | In Stock | |
| 100 mg | $2,500 | In Stock |
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Purity:98.02%
ee:100%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | HBDDE is a selective model inhibitor of the isoenzymes PKCα and PKCγ with IC 50 s of 43 μM and 50 μM, respectively.HBDDE has a higher affinity for PKCα/PKCγ than the PKCδ, PKCβI, and PKCβII isoenzymes.HBDDE is a derivative of ellagic acid, which induces apoptosis in neuronal cells. HBDDE is a derivative of ellagic acid and induces apoptosis in neuronal cells. |
| Targets&IC50 | PKCγ:50 μM (IC50), PKCα:43 μM (IC50) |
| In vitro | HBDDE (50 μM; 5 h; Cerebellar granule cells) leads to a substantial reduction in cell viability by approximately 70%. Additionally, HBDDE demonstrates a notable augmentation in caspase-3 activity.[1] |
| Molecular Weight | 338.31 |
| Formula | C16H18O8 |
| Cas No. | 154675-18-0 |
| Smiles | C(OC)C1=C(C(O)=C(O)C(O)=C1)C2=C(COC)C=C(O)C(O)=C2O |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||
| Solubility Information | DMSO: 4.5 mg/mL (13.3 mM) H2O: 0.9 mg/mL (2.7 mM) Ethanol: 0.9 mg/mL (2.7 mM) | ||||||||||
Solution Preparation Table | |||||||||||
H2O/Ethanol/DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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