Powder: -20°C for 3 years | In solvent: -80°C for 1 year
HIF-2α-IN-3 is an allosteric inhibitor of HIF-2α (IC50: 0.4 μM; KD: 1.1 μM) with anticancer activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 297.00 | |
25 mg | In stock | $ 987.00 | |
50 mg | In stock | $ 1,360.00 | |
100 mg | In stock | $ 1,860.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 318.00 |
Description | HIF-2α-IN-3 is an allosteric inhibitor of HIF-2α (IC50: 0.4 μM; KD: 1.1 μM) with anticancer activity. |
Targets&IC50 | HIF2α:(kd)1.1 µM , HIF2α:0.4 µM |
In vitro | HIF-2α-IN-3 ?inhibit HIF-2α-ARNT heterodimerization by binding an internal cavity of the HIF-2α PAS-B domain. |
Molecular Weight | 335.66 |
Formula | C12H6ClN5O5 |
CAS No. | 313964-19-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 12.5 mg/mL (37.24 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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HIF-2α-IN-3 313964-19-1 Angiogenesis Chromatin/Epigenetic HIF HIF-2a-IN-3 HIF-2alpha-IN-3 HIF2αIN3 HIF 2α IN 3 inhibitor inhibit