Powder: -20°C for 3 years | In solvent: -80°C for 1 year
HPK1-IN-7 is an orally active HPK1 inhibitor. It shows selectivity against IRAK4 (59 nM) and GLK (140 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 129.00 | |
2 mg | In stock | $ 189.00 | |
5 mg | In stock | $ 293.00 | |
10 mg | In stock | $ 483.00 | |
25 mg | In stock | $ 789.00 | |
50 mg | In stock | $ 1,080.00 | |
100 mg | In stock | $ 1,490.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 293.00 |
Description | HPK1-IN-7 is an orally active HPK1 inhibitor. It shows selectivity against IRAK4 (59 nM) and GLK (140 nM). |
Targets&IC50 | FLT3:25.4 nM (IC50), AMPK α1:44.3 nM (IC50), c-Kit:45.7 nM (IC50), FMS:3.2 nM (IC50), ICK:65.1 nM (IC50), IRAK4:59 nM (IC50), MST2:78.5 nM (IC50), HPK1:2.6 nM (IC50), MST1:55.1 nM (IC50), GLK/MAP4K3:140 nM (IC50) |
Molecular Weight | 458.47 |
Formula | C24H22N6O4 |
CAS No. | 2320462-65-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 125 mg/mL (272.65 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
HPK1-IN-7 2320462-65-3 MAPK HPK1 IN 7 MC38 Inhibitor PD1 HPK1IN7 tumor model oral selectivity HPK-1-IN-7 MAP4K inhibit MAPK Kinase Kinase Kinase inhibitor