Powder: -20°C for 3 years | In solvent: -80°C for 1 year
LGD-6972 is an antagonist of glucagon receptor.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 100.00 | |
5 mg | In stock | $ 241.00 | |
10 mg | In stock | $ 357.00 | |
25 mg | In stock | $ 589.00 | |
50 mg | In stock | $ 858.00 | |
100 mg | In stock | $ 1,180.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 346.00 |
Description | LGD-6972 is an antagonist of glucagon receptor. |
In vivo | LGD-6972 is well tolerated at the doses tested without dose-related or clinically meaningful changes in clinical laboratory parameters. No subject experiences hypoglycaemia.LGD-6972 has linear plasma pharmacokinetics consistent with once daily dosing that is comparable in healthy and T2DM subjects.?Dose-dependent decreases in fasting plasma glucose are observed in all groups with a maximum of 3.15 mM (56.8 mg/dL) on day 14 in T2DM subjects.?LGD-6972 also reduces plasma glucose in the postprandial state.?Dose-dependent increases in fasting plasma glucagon are observed, but glucagon levels decrease and insulin levels increase after an oral glucose load in T2DM subjects. |
Molecular Weight | 702.9 |
Formula | C43H46N2O5S |
CAS No. | 1207989-09-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 31 mg/mL (44.10 mM)
You can also refer to dose conversion for different animals. More
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LGD-6972 1207989-09-0 GPCR/G Protein Glucagon Receptor Inhibitor hyperglycaemia GCGR Diabetes cAMP glucagon LGD 6972 LGD6972 inhibit inhibitor