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Lindleyin

Catalog No. TN1052   CAS 59282-56-3

Lindleyin is a novel phytoestrogen and might trigger many of the biological responses evoked by the physiological estrogens.

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Lindleyin Chemical Structure
Lindleyin, CAS 59282-56-3
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1 mg In stock $ 132.00
5 mg In stock $ 323.00
10 mg In stock $ 480.00
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1 mL * 10 mM (in DMSO) In stock $ 330.00
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Purity: 99.74%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Lindleyin is a novel phytoestrogen and might trigger many of the biological responses evoked by the physiological estrogens.
In vitro One herbal extract, Rhei rhizoma (rhubarb), acts as an agonist to both ERalpha and ERbeta. The phytochemical Lindleyin, a major component of rhubarb, might contribute to this estrogenic activity through ERalpha and ERbeta. 4-Hydroxytamoxifen, an ER antagonist, completely reversed the estrogenic activity of Lindleyin. Lindleyin binds to ERalpha in vitro, as demonstrated using a fluorescent polarization assay. The in vivo effect of rhubarb extract was studied using a vitellogenin assay system in the freshwater fish, Japanese medaka (Oryzias latipes). There were marked increases in serum vitellogenin levels in male medaka exposed to rhubarb extract[1]
Source
Molecular Weight 478.45
Formula C23H26O11
CAS No. 59282-56-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. The phytochemical lindleyin, isolated from Rhei rhizoma, mediates hormonal effects through estrogen receptors.J Endocrinol. 2002 Nov;175(2):289-96.

Related compound libraries

This product is contained In the following compound libraries:
Rare Natural Compound Library

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Keywords

Lindleyin 59282-56-3 Endocrinology/Hormones Estrogen/progestogen Receptor Estrogen Receptor/ERR Inhibitor inhibit inhibitor

 

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