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Lindleyin is a novel phytoestrogen and might trigger many of the biological responses evoked by the physiological estrogens.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $132 | In Stock | |
5 mg | $323 | In Stock | |
10 mg | $480 | In Stock | |
25 mg | Inquiry | In Stock | |
50 mg | Inquiry | In Stock | |
1 mL x 10 mM (in DMSO) | $330 | In Stock |
Description | Lindleyin is a novel phytoestrogen and might trigger many of the biological responses evoked by the physiological estrogens. |
In vitro | One herbal extract, Rhei rhizoma (rhubarb), acts as an agonist to both ERalpha and ERbeta. The phytochemical Lindleyin, a major component of rhubarb, might contribute to this estrogenic activity through ERalpha and ERbeta. 4-Hydroxytamoxifen, an ER antagonist, completely reversed the estrogenic activity of Lindleyin. Lindleyin binds to ERalpha in vitro, as demonstrated using a fluorescent polarization assay. The in vivo effect of rhubarb extract was studied using a vitellogenin assay system in the freshwater fish, Japanese medaka (Oryzias latipes). There were marked increases in serum vitellogenin levels in male medaka exposed to rhubarb extract[1] |
Molecular Weight | 478.45 |
Formula | C23H26O11 |
Cas No. | 59282-56-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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